小剂量布地奈德气雾剂吸入治疗支气管哮喘的临床疗效  

Clinical Curative Effect of Low-Dose Budesonide Aerosol Inhalation in Treatment of Bronchial Asthma

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作  者:李成萍 LI Chengping(Xining City Chengzhong District Shenjiazhai Central Health Center,Xining,Qinghai,810001)

机构地区:[1]青海省西宁市城中区沈家寨中心卫生院,青海西宁810001

出  处:《智慧健康》2023年第10期181-185,共5页Smart Healthcare

摘  要:目的分析与研究对支气管哮喘采用布地奈德气雾剂(小剂量)治疗的效果。方法研究对象为本院收治的80例患者,均确诊为支气管哮喘,纳入期限为2019年10月-2021年10月,通过随机数字表法将其分为两组,对照组(n=40)和观察组(n=40)。对照组采用常规药物治疗,观察组采用布地奈德气雾剂(小剂量)进行治疗。两组均接受为期三个月的治疗。将两组治疗效果、治疗前后气道阻力、气道传导率、肺功能相关指标[第一秒用力呼气容积(FEV1)、呼气流速峰值(PEF)、用力肺活量(FVC)]、症状恢复情况及用药安全性实施比较。结果两组治疗效果差异显著,观察组优于对照组(P<0.05)。治疗后观察组气道阻力、气道传导率及肺功能相关指标均优于对照组(P<0.05)。观察组肺部哮鸣音减轻时间、喘憋减轻时间及住院时间均显著短于对照组(P<0.05)。观察组不良反应发生率显著低于对照组(P<0.05)。结论布地奈德气雾剂(小剂量)吸入治疗支气管哮喘效果良好,能够改善患者相关症状,促进其恢复,改善肺功能情况,且具有良好的安全性,值得临床推广应用。Objective To analyze and study application effect of budesonide aerosol(low dose)on bronchial asthma.Methods The paper chose 80 patients diagnosed with bronchial asthma admitted to our hospital from October 2019 to October 2021 as study objects,and divided them into two groups with random number table method:control group(n=40)and observation group(n=40).Control group was treated with routine drugs,while observation group with budesonide aerosol(low dose).Both groups was treated with treatment for three months.Treatment effect,airway resistance before and after treatment,airway conductivity,lung function related indicators[forced expiratory volume in the first second(FEV1),peak expiratory flow rate(PEF),forced vital capacity(FVC)],symptom recovery and drug safety were compared between two groups.Results There was significant difference in treatment effect between two groups,that of observation group was better than control group(P<0.05).After treatment,airway resistance,airway conductivity,and lung function related indicators of observation group were better than control group(P<0.05).Reducing time of lung wheezing,asthma,and length of stay in observation group was significantly shorter than control group(P<0.05).Incidence of adverse reactions in observation group was significantly lower than control group(P<0.05).Conclusion Budesonide aerosol(low dose)inhalation can achieve good curative effect on bronchial asthma,can improve related symptoms,promote recovery,improve lung function of patients with good safety,which is worthy of clinical promotion and application.

关 键 词:支气管哮喘 小剂量 布地奈德气雾剂 吸入治疗 临床疗效 

分 类 号:R562.25[医药卫生—呼吸系统]

 

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