生物制剂治疗银屑病后出现多发性雀斑样痣1例  

Multiple Lentigines Confined to Psoriatic Plaques During Treatment with Secukinumab:A Case Report

作　　者：刘俐 崔炳南[1] 王俊慧[1] LIU Li;CUI Bingnan;WANG Junhui(Department of Dermatology,Guang′anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)

机构地区：[1]中国中医科学院广安门医院皮肤科,北京100053

出　　处：《中国皮肤性病学杂志》2022年第11期1319-1321,共3页The Chinese Journal of Dermatovenereology

基　　金：中国中医科学院科技创新工程(重大攻关项目)(CI2021A02314)

摘　　要：患者女,48岁,四肢躯干红斑鳞屑反复20年。患者皮疹控制不佳,经感染性筛查后接受司库奇尤单抗标准治疗方案,约2个月后在原银屑病皮损消退的区域出现了多发的褐色斑点。皮肤镜示:均一淡褐色皮损,边缘不规则。诊断为雀斑样痣。A 48-year-old female presented with psoriasis plaques of 25 years′ duration. After many unsatisfying therapy, the patient underwent treatment with Secukinumab.After 2 months of treatment, the psoriasis plaques had disappeared, but in their place multiple brown lesions were seen.Dermoscopy: uniform pale brown lesions with irregular margins. The diagnosis was lentigines.

关 键 词：银屑病 司库奇尤单抗 IL-17 黑素细胞 雀斑样痣 

分 类 号：R758.63[医药卫生—皮肤病学与性病学] R758.51[医药卫生—临床医学]