新疆维吾尔自治区石河子市备孕期女性感染TORCH现状分析  

Situation analysis of TORCH infection among women during pregnancy preparation in Shihezi,Xinjiang Uygur Autonomous Region

作　　者：王丹 刘小甜 范开辉[2] 魏兴武[2] WANG Dan;LIU Xiao Tian;FAN Kai Hui;WEI Xing Wu(Medical College of Shihezi University,Shihezi 832000,Xinjiang Uygur Autonomous Region,China;Shihezi Maternal and Child Health Care Hospital,Shihezi 832000,Xinjiang Uygur Autonomous Region,China)

机构地区：[1]石河子大学医学院,新疆石河子832000 [2]石河子市妇幼保健院,新疆石河子832000

出　　处：《中国妇幼卫生杂志》2022年第1期45-48,共4页Chinese Journal of Women and Children Health

基　　金：新疆兵团八师石河子市2020重点人才项目(20205007)

摘　　要：目的探讨新疆维吾尔自治区石河子市备孕期女性感染病原体,包括弓形虫(toxoplasma,TOX)、其他病原体(others,O)、风疹病毒(rubella virus,RV)、巨细胞病毒(cytomegalo virus,CMV)、单纯疱疹病毒(herpes simplex virus,HSV),即TORCH现状,为石河子市妇女保健及优生优育工作提供数据支持。方法选取2017—2020年于新疆维吾尔自治区石河子市进行孕前健康检查的备孕期女性4721例为研究对象,其中风疹病毒、弓形虫、巨细胞病毒的感染情况采用常规胶体金法进行检测,乙型肝炎病毒、梅毒螺旋体(treponema pallidum,TP)、人类免疫缺陷病毒(human immunodeficiency virus,HIV)采用酶联免疫法检测,按备孕期女性的年龄、就诊的季节、年份分为不同组别进行感染情况的比较。结果在4721例调查对象中,HIV、TP、乙肝表面抗原(hepatitis B surface antigen,HBsAg)特异性抗体阳性率分别为0.02%、0.30%、4.43%;巨细胞病毒抗体免疫球蛋白M(immunoglobulin M,IgM)阳性率(3.00%)高于TOX-IgM(1.91%);RV-IgM阳性率最高(93.96%)。不同年龄组HBs Ag、风疹病毒免疫球蛋白G(immunoglobulin G,IgG)和CMV-IgG阳性率的差异具有统计学意义(P<0.05);除HBs Ag、HIV、TP、RV-IgG外,其他各病原体在不同季节检出率比较,差异均具有统计学意义(均P<0.05)。除HBs Ag、HIV、TP外,其他病原体阳性率在不同年份的差异均具有统计学意义(均P<0.05)。结论新疆维吾尔自治区石河子市存在不同年龄段及不同季节的TORCH易感人群,应采取相应的措施加强孕前健康检查,以预防新生儿先天性TORCH感染的发生,从而提高出生人口质量。Objective To investigate the pathogens that can easily cause fetal infection and abnormal development among women during pregnancy preparation including toxoplasma(TOX),others(O),rubella virus(RV),cytomegalovirus(CMV),and herpes simplex virus(HSV)(TORCH),and to provide data support for women and children’s health care in Shihezi City,Xinjiang Uygur Autonomous Region.Methods A total of 4721 women who underwent pre-pregnancy health examination in Shihezi City,Xinjiang Uygur Autonomous Region from 2017 to 2020 were recruited.RV,TOX and CMV were detected by conventional colloid gold method.hepatitis B virus(HBV),treponema pallidum(TP)and human immunodeficiency virus(HIV)were detected by enzyme-linked immunosorbent assay(ELISA).They were divided into different groups according to age,season and year for comparison.Results The positive rates of specific antibodies of HIV,TP and hepatitis B surface antigen(HBsAg)were 0.02%,0.30%and 4.43%in4721 cases,respectively.The positive rate of CMV-IgM(3.00%)was higher than that of TOX-IgM(1.91%).RV-IgM positive rate(93.96%)ranked the highest.The positive rates of HBs Ag,RV-IgG and CMV-IgG were different in various age groups(P<0.05).Except for HBs Ag,HIV,TP and RV-IgG,the detection rates of other pathogens were different in various seasons(allP<0.05).Except for HBs Ag,HIV and TP,the positive rates of other pathogens were different in various years(allP<0.05).Conclusion People are susceptible to TORCH in different ages and seasons in Shihezi City,Xinjiang Uygur Autonomous Region.Relevant measures should be taken to strengthen pre-pregnancy health examination in order to to prevent from congenital TORCH infection and improve the quality of newborns.

关 键 词：病原体 围产儿 备孕期女性 

分 类 号：R173[医药卫生—妇幼卫生保健]