气相色谱法测定工作场所空气中反式-1,1,1,4,4,4-六氟-2-丁烯  

Determination of trans-1,1,1,4,4,4-hexafluoro-2-butene in workplace air by gas chromatography

作　　者：胡嘉雯 陈嘉淳 袁静 吴凡 戎伟丰[1] 邵军丽 HU Jia-wen;CHEN Jia-chun;YUAN Jing;WU Fan;RONG Wei-feng;SHAO Jun-li(Guangdong Province Key Laboratory of Occupational Disease Prevention and Treatment,Guangdong Province Hospital for Occupational Disease Prevention and Treatment,Guangzhou,Guangdong 510300,China;不详)

机构地区：[1]广东省职业病防治院,广东省职业病防治重点实验室,广东广州510300 [2]广东医科大学公共卫生学院,广东东莞523808 [3]广东药科大学公共卫生学院,广东广州510310

出　　处：《中国职业医学》2022年第5期582-585,共4页China Occupational Medicine

基　　金：广东省自然科学基金(2020A1515010893);2021广东省本科高校教学质量与教学改革工程建设项目(粤教高涵[2021]29号);广东省职业病防治重点实验室(2017B030314152);广东医科大学2021年度课程思政教育教学研究专项(2SZ21011);2021年广东医科大学教学质量与教学改革工程项目(1JG21075)

摘　　要：目的建立工作场所空气中反式-1,1,1,4,4,4-六氟-2-丁烯[HFO-1366mzz(E)]的气相色谱测定方法。方法采用铝箔复合塑料袋采集工作场所空气中的HFO-1366mzz(E),直接进样,二甲基聚硅氧烷毛细管色谱柱分离,氢火焰离子化检测器检测,外标法定量。结果HFO-1366mzz(E)在质量浓度为6.82~68200.00 mg/m^(3)时呈现良好的线性关系,相关系数为0.9999。最低检出浓度为0.59 mg/m^(3),最低定量浓度为1.98 mg/m^(3)。加标回收率为95.45%~103.05%,批内、批间相对标准偏差分别为2.26%~5.07%和4.09%~6.82%。样品在室温下至少可保存7 d。结论本方法简单,线性范围广,检出限低,准确度、精密度较高,样品稳定性较好,可用于工作场所空气中HFO-1366mzz(E)的检测。Objective To establish a gas chromatographic method for the determination of trans-1,1,1,4,4,4-hexafluoro-2-butene[HFO-1366mzz(E)]in workplace air.Methods HFO-1366mzz(E)in air was directly collected with aluminum foil composite plastic bag,separated by dimethylpolysiloxane capillary column,detected by flame ionization detector,and quantified with external standard method.Results The linear range of HFO-1366mzz(E)was 6.82-68200.00 mg/m^(3),with the correlation coefficient of 0.9999.The detection limit and the lower limit of quantitation were 0.59 and 1.98 mg/m^(3),respectively.The recovery rate was within 95.45%-103.05%.The relative standard deviation of within-batch precision and between-batch precision were 2.26%-5.07%and 4.09%-6.82%,respectively.The samples can be stored at room temperature for at least seven days.Conclusion This method is simple to use with a wide linear range,low detection limit,high accuracy and precision and good sample stability.It can be used for the detection of HFO-1366mzz(E)in the air of workplace.

关 键 词：工作场所 空气 反式-1 1 1 4 4 4-六氟-2-丁烯 气相色谱法 

分 类 号：R134[医药卫生—劳动卫生]