脊髓灰质炎的流行现状及我国疫苗免疫策略的思考  

Current prevalence of poliomyelitis and consideration on polio vaccination strategies in China

作　　者：张淑君[1] 方明礼[1] 胡向科 黄铭华[1] 王志勇 杨彦华[1] 颜洁[1] 赖智维 高立冬[1] ZHANG Shu-jun;FANG Ming-li;HU Xiang-ke;HUANG Ming-hua;WANG Zhi-yong;YANG Yan-hua;YAN Jie;LAI Zhi-wei;GAO Li-dong(Hunan Provincial Center for Disease Control and Prevention,Changsha,Hunan 410005,China)

机构地区：[1]湖南省疾病预防控制中心,湖南长沙410005

出　　处：《实用预防医学》2022年第1期125-129,共5页Practical Preventive Medicine

摘　　要：现阶段,我国维持无脊髓灰质炎(简称脊灰)状态面临的挑战包括:脊灰野病毒(wild poliovirus,WPV)输入风险的存在、疫苗相关麻痹型脊髓灰质炎(vaccine associated paralytic poliomyelitis,VAPP)病例和脊髓灰质炎疫苗衍生病毒(vaccine-derived poliovirus,VDPV)病例的发生。有必要分析全球消灭脊灰形势的变化,并结合中国维持无脊灰工作进展和需要,就下阶段我国脊灰疫苗免疫策略提出参考建议。Currently,the challenges facing China in maintaining polio-free status include the risk of wild poliovirus(WPV)importation and the occurrence of vaccine-associated paralytic poliomyelitis(VAPP)and vaccine-derived poliovirus(VDPV)cases.It is necessary to put forward some suggestions for polio vaccination strategies in China in next stage via analyzing thechanges in global polio eradication situation and integrating the progress and demands in maintaining polio-free status in China.

关 键 词：脊髓灰质炎 脊髓灰质炎疫苗 疫苗免疫策略 疫苗相关麻痹型脊髓灰质炎 脊髓灰质炎疫苗衍生病毒 

分 类 号：R186[医药卫生—流行病学]