2003—2020年广州市19家市级流感监测哨点医院流感样病例监测分析  

Surveillance of influenza-like illness cases in 19 municipal sentinel hospitals for influenza monitoring in Guangzhou City, 2003-2020

作　　者：吴迪 曹蓝[1] 刘艳慧[1] 陈艺韵[1] 李魁彪[1] 陆剑云[1] WU Di;CAO Lan;LIU Yan-hui;CHEN Yi-yun;LI Kui-biao;LU Jian-yun(Guangzhou Municipal Center for Disease Control and Prevention,Guangdong,Guangzhou 510440,China)

机构地区：[1]广州市疾病预防控制中心,广东广州510440

出　　处：《实用预防医学》2022年第1期6-10,共5页Practical Preventive Medicine

基　　金：国家自然科学基金(81803325);广东省自然科学基金(2019A1515011407);广东省医学科研基金(A2019379,A2020399,B2021244);广州市卫生健康科技项目(20191A011064,20201A011062,20201A011067,20201A011062,20211A011059);广州市医学重点学科建设项目(2017-2019-07)

摘　　要：目的分析探讨广州市2003—2020年流感监测哨点医院流感样病例监测结果,为流感防控提供科学依据。方法通过中国疾病预防控制系统查询广州市历年流感报告病例数,报告发病率;通过广州市突发公共卫生事件监测与预警系统收集广州市各哨点医院历年流感样病例监测信息;并对上述信息进行描述性流行病学分析,使用分层资料的χ^(2)检验分析不同年份和不同性别流感发病情况的差异。结果自2008年起广州市累计监测门(急)诊就诊总人数10143万余人次,报告流感样病例503万余例,报告发病率自2015年以来持续增长(男性:χ^(2)=371894.146,P<0.001;女性:χ^(2)=366740.254,P<0.001),且男性总体发病率高于女性(χ^(2)=972.707,P<0.001)。流感样病例发病高峰期主要出现在1月、3—7月以及11—12月,各年份总体趋势大致相同;流感样病例主要年龄段为0~4岁组婴幼儿,5~14岁组儿童次之。流感报告病例主要集中于5~14组儿童,0~4岁组婴幼儿次之;流感报告病例男性高于女性,且差异有统计学意义(P<0.001)。流感病原学监测显示广州市主要流行毒株为A(H1N1)型(41.32%),A(H3N2)型次之(29.53%);不同年份优势毒株有所差异。结论广州市2003—2020年流感样病例流行呈季节性,流行强度有逐渐增强的趋势,且男性发病高于女性,但新型冠状病毒肺炎疫情防控常态化对于流感防控有积极作用。Objective To analyze and explore the surveillance results of influenza-like illness(ILI)cases in sentinel hospitals for influenza monitoring in Guangzhou City from 2003 to 2020 so as to provide a scientific basis for influenza prevention and control.Methods A descriptive epidemiological analysis was conducted based on the number of reported influenza cases and the reported morbidity of influenza in Guangzhou City from 2003 to 2020 collected through China Information System for Diseases Control and Prevention as well as the monitoring information about ILI cases in each sentinel hospital in Guangzhou City during 2003-2020 collected through the Monitoring and Early Warning System for Public Health Emergencies in Guangzhou City.A chi-square test based on hierarchical data was used to analyze the differences in the incidence of influenza in different years and different genders.Results A total of 101.43 million cases of outpatient(emergency)attendance in Guangzhou City were monitored cumulatively since 2008,and more than 5.03 million ILI cases were reported.The reported morbidity increased continuously since 2015(males:χ^(2)=371,894.146,P<0.001;females:χ^(2)=366,740.254,P<0.001),and the total morbidity of males was higher than that of females(χ^(2)=972.707,P<0.001).The incidence peak of ILI cases mainly occurred in January,March-July and November-December,and the general trend of each year was roughly the same.The main age group in ILI cases was infants aged 0-4 years,followed by children aged 5-14 years.The reported cases of influenza were mainly concentrated in children aged 5-14 years,followed by infants aged 0-4 years.The number of reported influenza cases was higher in males than in females,and the difference was statistically significant(P<0.001).Influenza etiological surveillance revealed that the main epidemic strain ofinfluenza in Guangzhou City was type A(H1 N1)(41.32%),followed by type A(H3 N2)(29.53%).The dominant strains weredifferent in different years.Conclusion The epidemic of ILI cases in Guangzho

关 键 词：流行性感冒 监测 流感样病例 发病率 哨点医院 

分 类 号：R511.7[医药卫生—内科学] R181.8[医药卫生—临床医学]