细菌性肝脓肿并发脓毒症相关危险因素分析  

Analysis of risk factors of bacterial hepatic abscess complicated with sepsis

作　　者：刘洋[1] 高敏 张劲夫 张兴文[2] 曾谷清[1] Liu Yang;Gao Min;Zhang Jinfu;Zhang Xingwen;Zeng Guqing(School of Nursing,University of South China;Emergency Department,Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University,Hunan Acute and Severe Clinical Research Center,Changsha,China)

机构地区：[1]南华大学护理学院 [2]湖南省人民医院(湖南师范大学附属第一医院)急诊医学科湖南省急危重症临床研究中心

出　　处：《实用休克杂志（中英文）》2022年第6期342-345,共4页Journal of Practical Shock

摘　　要：目的探讨细菌性肝脓肿并发脓毒症的相关危险因素。方法采用横断面研究方法,对2019年1月至2022年1月入住湖南省人民医院的细菌性肝脓肿患者进行回顾性分析。分为脓毒症组及非脓毒症组,比较两组间一般资料、实验室检验结果、影像学结果。通过单因素和多因素Logistic回归分析细菌性肝脓肿患者并发脓毒症的独立预测指标。结果901例细菌性肝脓肿患者中102例(11.3%)发生脓毒症;单因素Logistic回归分析显示,女性、WBC、PLT、CRP、PCT、ALB是细菌性肝脓肿导致发生脓毒症的相关因素(P<0.05);多因素Logistic回归模型发现女性发生脓毒症的风险是男性患者的0.43倍;CRP每增加1mg/L发生脓毒症的风险增加1%;ALB每增加1g/L发生脓毒症的风险下降19%;PCT每增加1ug/L发生脓毒症的风险增加1%;WBC每增加1×109/L发生脓毒症的风险增加6%。结论性别、CRP、ALB、PCT、WBC为细菌性肝脓肿发生脓毒症的独立预测因素。Objective To investigate the risk factors of bacterial liver abscess(BLA)complicated with sepsis.Methods A cross-sectional study was conducted to retrospectively analyze patients with BLA admitted to the Hospital of Hunan Province from January 2019 to January 2022.The patients were divided into sepsis group and non-sepsis group.The general data,laboratory test results and imaging results were compared between the two groups.Independent predictors of sepsis in patients with BLA were determined by univariate and multivariate Logistic regression analysis.Results Sepsis occurred in 102(11.3%)of 901 patients with pyogenic liver abscess;Univariate Logistic regression analysis showed that female,WBC,PLT,CRP,PCT,ALB were the related factors of BLA(P<0.05);A multivariate Logistic regression model found that women were 0.43 times more likely to develop sepsis than men;There was a 1%increased risk of sepsis per 1mg/L increase in CRP and a 19%decreased risk of sepsis per 1 mg/L increase in ALB.There was a 1%increased risk of sepsis per 1ug/L increase in PCT and a 6%increased risk of sepsis per 1×10~9/L increase in WBC.Conclusions Gender,CRP,ALB,PCT and WBC were independent predictors of sepsis in BLA.

关 键 词：细菌性肝脓肿 脓毒症 危险因素 

分 类 号：R459.7[医药卫生—急诊医学] R575.4[医药卫生—治疗学]