右美托咪定在颅内动脉瘤栓塞术苏醒期的应用效果分析  

Analysis of the Effect of Dexmedetomidine in the Recovery Period of Intracranial Aneurysm Embolization

作　　者：焦磊 蒋明[2] 周加浩[2] 方震[2] JIAO Lei;JIANG ming;ZHOU Jiahao;FANG Zhen(Department of Neurosurgery,People's Hospital of Lishui District,Nanjing 211200,China;Department of Neurosurgery,Affiliated Hospital of Jiangsu University,Zhenjiang 212001,China)

机构地区：[1]江苏省南京市溧水区人民医院神经外科,211200 [2]江苏大学附属医院神经外科,江苏省镇江市212001

出　　处：《实用心脑肺血管病杂志》2020年第S01期66-68,共3页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的研究右美托咪定在颅内动脉瘤栓塞术苏醒期的应用效果。方法选取2017年1月—2020年3月医院收治的颅内动脉瘤栓塞术患者30例,随机分为对照组和观察组,每组15例。对照组术后苏醒期使用安慰剂,观察组术后苏醒期使用右美托咪定。比较两组给药前后及吸痰拔管前后不同时段的心率、血压情况,同时比较两组拔管时间及呛咳评分。结果对照组吸痰拔管前心率(97.85±7.96)次/min、血压(99.98±5.10)mm Hg,吸痰拔管后心率(93.78±8.27)次/min、血压(96.72±4.91)mm Hg,与给药前后相比,差异均有统计学意义(P<0.05);观察组吸痰拔管前心率(84.98±6.18)次/min、血压(87.85±6.48)mm Hg,吸痰拔管后心率(83.48±7.24)次/min、血压(85.40±4.43)mm Hg,与给药前后相比,差异均无统计学意义(P>0.05)。两组拔管时间相比,差异无统计学意义(P>0.05);观察组呛咳评分(1.14±0.52)分、低于对照组的(3.26±1.23)分,差异有统计学意义(P<0.05)。结论在颅内动脉瘤栓塞术苏醒期,对患者使用右美托咪定,能够有效减少患者血流动力学异常变化,同时降低呛咳反射,不会增加拔管时间,应用效果十分理想。Objective To study the effect of dexmedetomidine in the recovery stage of intracranial aneurysm embolization.Methods 30 patients with intracranial aneurysm embolization admitted to the hospital from January,2017 to march,2020.03 were randomly divided into control group and observation group,with 15 patients in each group.Placebo was used in the control group and dexmedetomidine was used in the observation group.The heart rate and blood pressure of the two groups were compared before and after ad ministration and at different periods before and after sputum aspiration and extubation.Meanwhile,the extubation time and choking scores of the two groups were compared.Results The heart rate(97.85±7.96)/min,blood pressure(99.98±5.10)mm Hg before sputum aspiration and extubation,and the heart rate(93.78±8.27)/min,blood pressure(96.72±4.91)mm Hg after sputum aspiration and extubation were significantly different in the control group(P<0.05).In the observation group,there was no significant difference in heart rate(84.98±6.18)/min and blood pressure(87.85±6.48)mm Hg before sputum aspiration and extubation,and in heart rate(83.48±7.24)/min and blood pressure(85.40±4.43)mm Hg after sputum aspiration and extubation,compared with before and after ad ministration(P>0.05).There was no significant difference in extubation time between the two groups(P>0.05).The score of cough in the observation group was(1.14±0.52),which was lower than(3.26±1.23)in the control group,showing a significant difference(P<0.05).Conclusion Dexmedetomidine can effectively reduce the abnormal changes of hemodynamics,reduce the cough reflex,and not increase the extubation time in patients during the recovery period of intracranial aneurysm embolization.The application effect is very ideal.

关 键 词：右美托咪定 颅内动脉瘤 栓塞术 苏醒期 应用效果 

分 类 号：R614[医药卫生—麻醉学]