以脓疱为主要表现的Sweet综合征一例并文献复习  

Sweet's syndrome with pustules as the main symptom:a case report and review of the literature

作　　者：汪晴 邓小蓉[2] 吕静[2] 刘娟娟 WANG Qing;DENG Xiao-rong;LV Jing(the Second Clinical College,Guangzhou University of Chinese Medicine,Guangzhou,510120,China)

机构地区：[1]广州中医药大学第二临床医学院,510120 [2]重庆市中医院皮肤科·重庆市皮肤病临床医学研究中心

出　　处：《实用皮肤病学杂志》2023年第4期251-254,共4页Journal of Practical Dermatology

基　　金：重庆市皮肤病临床研究中心资助项目(cstc2015yfpt_gcjsyjzx120014)

摘　　要：67岁女性患者,双手皮损伴疼痛8 d,累及双踝部及足背6 d。皮肤科情况:双手足、踝部见多发米粒至绿豆大小红色丘疹,黄豆至鸡蛋大小水肿性红色斑块,部分丘疹及斑块上见散在或密集分布针尖至绿豆大小脓疱。实验室检查:外周血白细胞计数13.29×109/L、中性粒细胞百分比82.7%、C反应蛋白107.21 mg/L。皮损组织病理:表皮内脓疱形成,真皮层可见密集中性粒细胞浸润。诊断:Sweet综合征。予以糖皮质激素系统性治疗1个月后,皮损基本消退。随访8个月,皮损无复发。A 67-year-old female presented with rashes on her hands accompanied with pain for 8 days,which later involved her ankles and instep for 6 days.A dermatological examination revealed that multiple red papules ranging in size from rice grains to green beans,as well as edematous red patches ranging from the size of soybeans to eggs,visible on both hands,feet and ankles.Some papules and patches were scattered or densely distributed,varying in size from needle tips to green beans.Laboratory examination showed peripheral white blood cell count of 13.29×109/L,percentage of neutrophils at 82.7%and C-reactive protein level of 107.21 mg/L.Histopathological examination revealed an intraepidermal pustule and dense infiltration of neutrophils in the dermis.The diagnosis of sweet's syndrome was made.After being treated with systemic corticosteroid for a month,the skin lesions basically disappeared.No recurrence was observed during the 8-month follow-up period.

关 键 词：SWEET综合征 急性发热性嗜中性皮病 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]