制药工程专业实验阿法依伯汀的谱学分析与指认  

Spectroscopic Analysis and Identification of Alfaibertin in Pharmaceutical Engineering Specialty Experiments

作　　者：金洁 施琪浩 蒋鑫 章少阳 张嘉琪 董俊杰 洪文燕 秦利明 张英杰 钟爱国 JIN Jie;SHI Qi-hao;JIANG Xin;ZHANG Shao-yang;ZHANG Jia-qi;DONG Jun-jie;HONG Wen-yan;QIN Li-min;ZHANG Ying-jie;ZHONG Ai-guo(College of Pharmaceutical,Chemical and Materials Engineering,Taizhou University,Taizhou Zhejiang 318000,China)

机构地区：[1]台州学院医药化工与材料工程学院,浙江台州318000

出　　处：《当代化工》2020年第6期1107-1109,1113,共4页Contemporary Chemical Industry

基　　金：2019年度台州市大学生科技创新项目资助(项目编号:2019121)

摘　　要：利用Gaussion 09W软件在DTF/B3LYP 6-311+G水平下优化并计算了新型基因兴奋剂促红细胞生成素阿法依伯汀(EPO)的四大分子光谱:紫外-可见吸收光谱,红外吸收光谱,拉曼吸收光谱以及核磁共振吸收光谱;计算了22种常见单取代衍生物的氢和氧原子信息指数,讨论了其在马拉松运动员体液酸碱性(p Ka)检测中的预报应用。所得结果可协助对阿法依伯汀分子光谱理解及体液检测。Using Gaussion 09W software,the four macromolecular spectra of the novel gene stimulant EPO were optimized and calculated at DTF/B3LYP 6-311+G level:UV-Vis,IR,LM and 1HNMR,13CNM.R.Its specific application in marathon athletes'body fluid detection was discussed.The research is helpful for having a more perceptual understanding of the three-dimensional structure of erythropoietin molecule.

关 键 词：制药工程实验 基因兴奋剂 促红细胞生成素 谱学分析 

分 类 号：G822.8[文化科学—体育训练] TQ460.72-4[文化科学—体育学]