电针结合红外线照射对反复着床失败患者子宫内膜容受性、胚胎移植及妊娠情况的影响  

Effect of Electro-acupuncture Combined with Infrared Irradiation on Endometrial Receptivity, Embryo Transfer and Pregnancy in Patients with Repeated Implantation Failure

作　　者：赵萌 柳榴 权效珍[1] 兰艳丽[1] 田小龙[1] 吉志松 杨学舟[1] ZHAO Meng;LIU Liu;QUAN Xiao-zhen;LAN Yan-li;TIAN Xiao-long;JI Zhi-song;YANG Xue-zhou(Reproductive Medicine Centre,Affiliated Hospital of Hubei Academy of Arts and Sciences/Xiangyang Central Hospital of Hubei Province,Xiangyang,Hubei,441021,China;Department of Gynecology Ⅲ,People's Hospital ofWuhan University,Wuhan,Hubei,430060,China)

机构地区：[1]湖北文理学院附属医院/湖北省襄阳市中心医院生殖医学中心,湖北襄阳441021 [2]武汉大学人民医院妇Ⅲ科,湖北武汉430060

出　　处：《现代生物医学进展》2019年第23期4549-4552,4535,共5页Progress in Modern Biomedicine

基　　金：湖北省卫生计生委2016-2017年度中医药中西医结合科研一般项目(鄂卫生计生通2017-20号);湖北省自然科学基金项目(2018CFB472).

摘　　要：目的:观察电针结合红外线照射对反复着床失败(RIF)患者子宫内膜容受性、胚胎移植及妊娠情况的影响。方法:选取102例于2015年5月-2018年5月在我院行复苏胚胎移植的RIF患者,按照随机数字表法将患者分为电针结合红外线照射治疗组(A组,38例)、安慰针刺组(B组,34例)及空白对照组(C组,30例)。比较三组治疗前后血清雌二醇、孕酮水平,于治疗前后检测子宫内膜容受性超声学指标,包括子宫内膜厚度、内膜容积、血管血流指数(VFI)、内膜血流指数(FI)、阻力指数(RI),比较三组胚胎移植及妊娠情况。结果:三组治疗前后血清雌二醇、孕酮水平比较无统计学差异(P>0.05)。治疗后A组子宫内膜厚度、内膜容积大于治疗前及B组、C组,VFI、FI高于治疗前及B组、C组,RI低于治疗前及B组、C组(P<0.05)。三组移植胚胎数、生化妊娠率、临床妊娠率比较无统计学差异(P>0.05),A组胚胎着床率高于B组、C组(P<0.05)。结论:电针结合红外线照射治疗RIF患者可以改善子宫内膜容受性,提高胚胎着床率。Objective:To observe the effect of electro-acupuncture combined with infrared irradiation on endometrial receptivity,embryo transfer and pregnancy in patients with repeated implantation failure(RIF).Methods:102 RIF patients who underwent resuscitation embryo transfer in our hospital from May 2015 to May 2018 were selected.According to the random number table method,the patients were divided into electro-acupuncture combined with infrared irradiation treatment group(group A,38 cases),placebo acupuncture group(group B,34 cases)and blank control group(group C,30 cases).The levels of serum estradiol and progesterone were compared before and after treatment among three groups,endometrial receptive ultrasound were measured before and after treatment,including endometrial thickness,endometrial volume,vascularization flow index(VFI),flow index(FI)resistance index(RI),embryo transfer and pregnancy were compared among three groups.Results:There was no significant difference in serum estradiol and progesterone levels among three groups before and after treatment(P>0.05).After treatment,the endometrial thickness,endometrial volume in group A were larger than those before treatment,group B and group C,VFI and FI were higher than those before treatment,group B and group C,RI was lower than those before treatment,group B and group C(P<0.05).There was no significant difference in the number of embryos transferred,biochemical pregnancy rate and clinical pregnancy rate among three groups(P>0.05),the implantation rate in group A was higher than that in group B and C(P<0.05).Conclusion:Electro-acupuncture combined with infrared irradiation can improve endometrial receptivity and embryo implantation rate in RIF patients.

关 键 词：电针 红外线照射 反复着床失败 子宫内膜容受性 妊娠 

分 类 号：R714.8[医药卫生—妇产科学]