中药炮制“炭药止血”理论的现代研究进展  

Modern Research Progress on the Theory of“Carbonic Herbs for Hemostasis”in Chinese Materia Medica

作　　者：张贺 徐园园 王明慧 辛义周[1,2] 马传江[1,2] 魏永利[1,2] Zhang He;Xu Yuanyuan;Wang Minghui;Xin Yizhou;Ma Chuanjiang;Wei Yongli(Grade Three Laboratory of Traditional Chinese Medicine Preparation of State Administration of Traditional Chinese Medicine,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011,China;Laboratory for Molecular Identification and Biological Evaluation of Chinese Herbal Pieces,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011,China;College of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)

机构地区：[1]山东中医药大学附属医院·国家中医药管理局中药制剂三级实验室,济南250011 [2]山东中医药大学附属医院·中药饮片分子鉴定与生物评价实验室,济南250011 [3]山东中医药大学药学院,济南250355

出　　处：《世界科学技术-中医药现代化》2023年第4期1502-1510,共9页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家中医药管理局中药炮制技术传承基地建设项目(2016-2-11):中药炮制技术传承基地建设项目(山东中医药大学附属医院),负责人:马传江

摘　　要：炭药在中医临床上常用于治疗各种出血性疾病,中药炮制“炭药止血”理论在炭药的选用中占有重要地位。目前有关“炭药止血”理论的物质基础研究尚不充分,对中药炒炭后的止血效果也存有争议。本文从止血物质基础、药效学、止血机制3个方面对该理论研究进展进行归纳和总结,并对止血物质基础研究中的新思路“纳米类成分”进行探讨,以期为“炭药止血”理论的深入研究提供参考,为中医临床合理选用炭药提供依据。Carbonic herbs are commonly used in the treatment of various hemorrhagic diseases in clinics,and the theory of"carbonic herbs for hemostasis"plays an important role in the selection of carbonic herbs.At present,the material basis of the theory of"carbonic herbs for hemostasis"has not been fully researched,and there are controversies about the hemostatic effect of Chinese materia medica after carbonization.In this paper,the research progress of this theory was summarized and concluded from three aspects of material basis,pharmacodynamics,and hemostatic mechanism,and the new idea of"nano-components"in the study of material basis was also reported.The review provided the reference for further research on the theory of'carbonic herbs for hemostasis'and also provided a basis for the clinical rational use of carbonic herbs.

关 键 词：炭药止血 物质基础 止血机制 中药炮制 纳米类成分 

分 类 号：R283.1[医药卫生—中药学]