老年慢性心衰患者抗心衰治疗后血浆脑利钠肽水平分布及影响因素评价  

Distribution of Plasma Brain Natriuretic Peptide Levels and Its Influencing Factors in Elderly Patients with Chronic Heart Failure after Anti-heart Failure Treatment

作　　者：王雄飞 WANG Xiong-fei(Department of Cardiology,First People's Hospital of Honghe Prefecture,Mengzi,Yunnan Province,661100 China)

机构地区：[1]云南省红河州第一人民医院心血管内科,云南蒙自661100

出　　处：《世界复合医学》2020年第1期39-41,共3页World Journal of Complex Medicine

摘　　要：目的研究分析老年慢性心衰患者经过抗心衰治疗后的血浆脑利钠肽水平以及影响因素。方法选择50例该院所收治的老年慢性心衰患者以及50名在该院健康体检的正常人群作为研究对象,2017年10月—2018年10月作为该研究的时间范围,对这些患者的临床相关资料进行回顾性分析。将这些患者分为观察组以及参照组,观察组患者为老年慢性心衰患者,参照组为该院体检的健康人群。比较两组患者的收缩压、舒张压、肺淤血、肺动脉高压以及左室射血分数。比较观察组患者在抗心衰治疗前后的BNP水平,由此来判断抗心衰的治疗效果以及老年慢性心衰患者经过抗心衰治疗后的血浆脑利钠肽水平以及影响因素。结果观察组患者的收缩压、舒张压、肺淤血例数、肺动脉高压以及左室射血分数[(129.20±17.73)mmHg,(61.27±6.44)mmHg,12例,(37.25±8.24)mmHg,(34.68±10.22)%]相比于参照组数值较高,差异有统计学意义(t=3.912、6.144、5.488、6.108,χ~2=13.636,P<0.05)。观察组患者在抗心衰治疗前后[(653.79±131.47)ng/L vs(512.68±128.34)ng/L]的BNP水平变化较大,治疗前后的差异有统计学意义(χ~2=5.430,P<0.05)。结论抗心衰治疗可以有效的改善患者的BNP水平,收缩压、肺淤血等因素是老年慢性心衰患者血浆脑利钠肽水平分布的重要影响因素。Objective To study the plasma levels of brain natriuretic peptide and its influencing factors in elderly patients with chronic heart failure after anti-heart failure treatment.Methods A total of 50 elderly patients with chronic heart failure admitted to our hospi-tal and 50 normal healthy subjects in our hospital were selected as subjects.From October 2017 to October 2018,as the time frame of the study,these patients were included.Clinically relevant data were retrospectively analyzed.The patients were divided into an ob-servation group and a reference group.The observation group was a chronic heart failure patient in the elderly,and the reference group was a healthy person in our hospital.Systolic blood pressure,diastolic blood pressure,pulmonary congestion,pulmonary hyper-tension,and left ventricular ejection fraction were compared between the two groups.The BNP level of patients in the observation group before and after anti-heart failure treatment was used to judge the therapeutic effect of anti-heart failure and the plasma brain natriuretic peptide level and influencing factors after anti-heart failure treatment in elderly patients with chronic heart failure.Results(1)Compared with the systolic blood pressure,diastolic blood pressure,pulmonary congestion,pulmonary hypertension,and left ven-tricular ejection fraction[(129.20±17.73)mmHg,(61.27±6.44)mmHg,12 case,(37.25±8.24)mmHg,(34.68±10.22)%].The reference group values were higher,The difference was statistically significant(t=3.912,6.144,5.488,6.108,χ~2=13.636.P<0.05).The BNP level of the observation group patients before and after anti-heart failure treatment[(653.79±131.47)]ng/L vs(512.68±128.34)ng/L]was significantly different,The difference before and after treatment was statistically significant(χ~2=5.430.P<0.05).Conclusion Anti-heart failure treatment can effectively improve the BNP level of patients.Systolic blood pressure,pulmonary congestion and other factors are important factors influencing the distribution of plasma brain natriuretic pept

关 键 词：老年慢性心衰患者 抗心衰治疗 血浆脑利钠肽水平 影响因素 

分 类 号：R541.6[医药卫生—心血管疾病]