基于因子分析的宫颈高危型人乳头瘤病毒感染证素研究  

Study on syndrome elements of cervical high risk human papillomavirus infection based on factor analysis

作　　者：刘君 李娅 马秀丽[2] 滕秀香[1] 薛晓鸥[2] LIU Jun;LI Ya;MA Xiuli;TENG Xiuxiang;XUE Xiaoou(Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China;Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Hangzhou Lin’an TCM Hospital,Hangzhou 311300,Zhejiang,China)

机构地区：[1]首都医科大学附属北京中医医院,北京100010 [2]北京中医药大学东直门医院,北京100700 [3]杭州市临安区中医院,浙江杭州311300

出　　处：《上海中医药杂志》2022年第8期27-29,36,共4页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(81774360)

摘　　要：目的探讨宫颈高危型人乳头瘤病毒(HR-HPV)感染患者的中医证素分布特征,为其临床辨证论治提供客观依据。方法采用流行病学研究方法,收集210例宫颈HR-HPV感染患者的四诊及相关信息,通过因子分析方法提取相关证候要素。结果通过因子分析共提取14个公因子,累积方差贡献率为75.99%。结果表明,宫颈HR-HPV感染者病位证素主要为胞宫、脾、肾、肝、心,病性证素主要为湿、热、阳虚、气虚、气滞、阴虚、血瘀。结论本研究因子分析结果在一定程度上反映了宫颈HR-HPV感染的主要证素特点,对该病的证候研究有一定参考价值。Objective To investigate the distribution characteristics of traditional Chinese medicine syndrome elements in patients with cervical high risk human papillomavirus(HR-HPV)infection,in order to provide the objective evidence for its syndrome differentiation and treatment.Methods The method of epidemiological study was applied.Four diagnoses and its related information of 210 patients with cervical HR-HPV infection were collected,and the related syndrome essential factors were extracted by factor analysis method.Results A total of 14 common factors were extracted by factor analysis,and the cumulative variance contribution rate was 75.99%.The results showed that,the main disease location syndrome elements of patients with cervical HR-HPV infection were uterus,spleen,kidney,liver and heart,and the main disease nature syndrome elements were dampness,heat,yang deficiency,qi deficiency,qi stagnation,yin deficiency and blood stasis.Conclusion The results of factor analysis in this study reflect the main characteristics of the syndrome elements of cervical HR-HPV infection to a certain extent,and have a certain reference value for the syndrome study of this disease.

关 键 词：人乳头瘤病毒 宫颈癌 因子分析 证素 辨证论治 

分 类 号：R271.9[医药卫生—中西医结合]