石氏强筋功法联合密骨胶囊治疗骨量减少的慢性非特异性下腰痛随机对照研究  

Shi’s exercise of strengthening muscles combined with Migu Capsules in treating chronic non-specific low back pain with bone loss:A randomized controlled study

作　　者：廉由之 邓真 李国中 商海滨 陈蓓 陈博[2,3] 詹红生[2,3] LIAN Youzhi;DENG Zhen;LI Guozhong;SHANG Haibin;CHEN Bei;CHEN Bo;ZHAN Hongsheng(Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai 201999,China;Shi’s Center of Orthopedics and Traumatology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Institute of Traumatology&Orthopedics,Shanghai Academy of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海市宝山区中西医结合医院,上海201999 [2]上海中医药大学附属曙光医院石氏伤科医学中心,上海201203 [3]上海市中医药研究院骨伤科研究所,上海201203

出　　处：《上海中医药杂志》2020年第S01期101-105,共5页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81804114);上海市科委科研计划医学重点项目(16401970102);上海市科委“科技创新行动计划”生物医药领域产学研医合作项目(17DZ920200);上海市重中之重临床重点学科建设项目(2017ZZ02024);上海市中医药新兴交叉学科资助计划项目[(沪卫计中发2017(024)号);上海市卫健委科研资助项目(ZYKC201602006);上海市卫健委临床行业专项项目(201840004).

摘　　要：目的观察石氏强筋功法联合密骨胶囊治疗慢性非特异性下腰痛(CNLBP)伴骨量减少的临床疗效。方法纳入90例CNLBP伴骨量减少(肝肾不足证)患者,采用随机对照的试验设计方法,分为A组、B组和C组,每组各30例。3组患者均予密骨胶囊口服,治疗周期为26周;B组患者在此基础上联合石氏强筋功法锻炼,治疗周期为12周;C组患者在此基础上联合核心稳定训练,治疗周期为12期。比较3组患者治疗前后的疼痛数字评分法(NRS)评分、腰椎功能障碍指数(ODI)评分,检测所有患者的骨密度。结果治疗8周、12周、26周后,3组患者的NRS评分、ODI评分均显著低于入组时(P<0.05),且B组、C组患者的评分均低于A组(P<0.05),B组和C组患者的评分比较差异无统计学意义(P>0.05)。治疗后,90例受试者的股骨颈、髋部骨密度上升明显。结论石氏伤科强筋功法联合密骨胶囊能有效改善CNLBP伴骨量减少患者的疼痛和功能活动,并维持骨量,疗效较佳,适合临床推广应用。Objective To study the clinical efficacy of Shi’s exercise of strengthening muscles combined with Migu Capsules in treating chronic non-specific low back pain(CNLBP)with bone loss.Methods Ninety CNLBP cases with bone loss(syndrome of deficiency of liver and kidney)were included.A randomized,controlled trial was performed.The patients were divided in the group A,group B and group C,30 cases in each group.All patients were orally treated with Migu Capsules,with a treatment course of 26 weeks.Based on this,the group B was treated with Shi’s exercise of strengthening muscles for 12 weeks,and the group C was treated with core stability training for 12 courses.The number rating scale(NRS)score and Oswestry disability index(ODI)score in the three groups were compared before and after treatment,and the bone mineral density was detected in all patients.Results After treatment for 8,12 and26 weeks,the NRS score and ODI score of the three groups were significantly decreased compared with treatment before(P<0.05),and the scores of the group B and group C were lower than those of the group A(P<0.05),there were no statistically significant differences in these scores between group B and group C(P>0.05).After treatment,the bone mineral density of femoral neck and hip was increased significantly in 90 subjects.Conclusion Shi’s exercise of strengthening muscles combined with Migu Capsule can effectively improve the pain and functional activities in patients of chronic non-specific low back pain with bone loss,and maintain the bone mass,which shows good efficacy and worthy of clinical promotion and application.

关 键 词：慢性非特异性下腰痛 骨量减少 强筋功法 核心稳定运动 密骨胶囊 

分 类 号：R274.9[医药卫生—中西医结合]