结直肠癌转移的中医理论构想  

Theoretical conception of traditional Chinese medicine for metastasis of colorectal cancer

作　　者：林怡 陶丽[1] LIN Yi;TAO Li(Department of Oncology,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]上海中医药大学附属龙华医院肿瘤科,上海200032

出　　处：《上海中医药杂志》2020年第2期6-9,共4页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金青年基金项目(81603548);国家卫计委医药卫生科技发展研究中心“重大新药创制”科技重大专项(2017ZX09304001).

摘　　要：结直肠癌患者死亡的主要原因是侵袭转移,因此控制其转移对延长晚期结直肠癌患者的生存期具有重要意义。从病因病机出发,结合古典医籍、各家学说、临床与基础实验文献,提出结直肠癌转移的中医理论构想:正气亏虚(尤其是脾虚)是内在根本,癌毒内结(痰、瘀、毒、潜伏下来的致病因子)是必要条件,经络传注是主要途径,诱因则可成为导火索,最终造成癌毒在经络之间、脏腑之间、经络脏腑之间的传变。认为防治结直肠癌侵袭转移当以健脾为主,结合各种祛邪手段(化痰、软坚、解毒、化瘀等),修复受损之络脉。The main cause of death in colorectal cancer is invasion and metastasis.It is important to control the metastasis for prolonging the survival period of patients with advanced colorectal cancer.Based on the etiology and pathogenesis,combined with classical medical records,various medical theories,clinical and basic experimental literature,this paper puts forward the TCM concept of recurrence and metastasis of colorectal cancer.Deficiency of healthy qi(especially spleen deficiency)is its internal root cause,cancer toxin(phlegm,blood stasis,toxin,latent pathogenic factor)is its necessary condition,meridian transmission and injection is its main way,and inducement can be the fuse.Finally,it causes the transmission of cancer toxin between meridians and collaterals,Zang organs and Fu organs,and meridians and Zang-Fu organs.It is proposed that the prevention and treatment of colorectal cancer invasion and metastasis should be based on strengthening the spleen,combining with various means of eliminating pathogenic factors(reducing phlegm,softening hardness,detoxifying,removing stasis,etc.)to repair the damaged collaterals.

关 键 词：结直肠癌 转移 病因病机 正气亏虚 癌毒内结 经络传注 中医药疗法 

分 类 号：R273[医药卫生—中西医结合]