正常孕妇20~42周各孕周24小时尿雌三醇和肌酐排泄量的关系  

RELATIONSHIP BETWEEN 24-HOUR URINE ESTRIOL AND CREATININE EXCRETIONS IN 20TH TO 42ND WEEKS OF NORMAL GESTATION

作　　者：赵右更[1] 周祖琴 洪丽娟 袁美英[1] 杨桂珍 

机构地区：[1]中国福利会国际和平妇幼保健院

出　　处：《上海医学》1983年第11期638-642,共5页Shanghai Medical Journal

摘　　要：24小时尿雌三醇值是了解胎儿胎盘功能单位的较好指标之一。但收集24小时尿不完整率高达50%,可导致雌三醇值偏低,干扰临床诊断。为此,我们测定72例正常孕妇20~42周各孕周24小时尿标本498份的雌三醇(E)及肌酐(C)值,以了解两者的关系。结果表明:1.各孕周尿肌酐均值相对稳定,其正常范围为0.60~1.40g/24h。凡是尿量收集完整的标本肌酐值都大于0.60g/24h。2.经测定肌酐值校对的尿标本基础上,建立了本院实验室正常妊娠20~42周各孕周E值及E/C比值的均数曲线。两者呈高度相关(r=0.994);对尿肌酐值偏离1愈多者,应用E/C比值后其变异度较E者可减少一半以上。可以认为E/C比值更能合理反映胎儿胎盘功能。A total of 498 urine specimens were collected from 72 normal pregnant women at 20th to 42nd weeks gestation;estriol and creatinine values were measured to determine the relationship between the two.The results revealed:1.The normal range of urinary creatinine values was between 0.6-1.4 g/24 hr.If the 24-hr urine creatinine value was less than 0.6 g/24 hr,the urine samples might have been incompletely collected.2.The curves of the normal mean values of urinary Eand E/C ratio from 20th to 42nd weeks of gestation were established.The two were closely correlated(r=0.994),E/Cis a parameter irrespective of urine volume,therefore,the E/C ratio is a more reliable index of fetoplacental function than the estriol value alone.

关 键 词：孕周 正常孕妇 雌三醇 雌甾三醇 排泄量 肌酐 

分 类 号：R71[医药卫生—妇产科学]