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作 者:秦红玲[1] 钟洁[1] 秦超[2] 吴原[2] 赵莉莉 陈炜[1] 梁妮[1] 胡跃强[1] QIN Hongling;ZHONG Jie;QIN Chao;WU Yuan;ZHAO Lili;CHEN Wei;LIANG Ni;HU Yueqiang(The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,Guangxi Zhuang Autonomous Region,China;The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China;Hospital of Guangxi Armed Police Corps,Nanning 530003,Guangxi Zhuang Autonomous Region,China)
机构地区:[1]广西中医药大学第一附属医院,广西壮族自治区南宁530023 [2]广西医科大学第一附属医院,广西壮族自治区南宁530021 [3]武警广西壮族自治区总队医院,广西壮族自治区南宁530003
出 处:《神经病学与神经康复学杂志》2022年第1期8-14,共7页Journal of Neurology and Neurorehabilitation
基 金:国家重大疑难疾病(脑梗死)中西医临床协作试点项目[国中医药办医政发(2018)3号]
摘 要:目的:观察扶阳三焦次第疗法治疗脑梗死的临床疗效。方法:收集2家医院(广西中医药大学第一附属医院和广西医科大学第一附属医院)2019年9月—2021年3月就诊的脑梗死患者60例,随机分为治疗组和对照组,每组各30例。对照组给予常规西医治疗,治疗组在常规西医治疗基础上联合中药治疗,均治疗4周。比较治疗前后的总有效率、中医证候评分、日常生活活动能力评分、简化Fugl-Meyer运动功能评分、美国国立卫生院神经功能缺损评分以及血清同型半胱氨酸水平。结果:治疗组有效率优于对照组,差异有统计学意义(P<0.05)。治疗后,2组患者的神经功能评分、中医证候评分和血清同型半胱氨酸水平均低于治疗前,且治疗组显著低于对照组(P<0.05);治疗后,2组患者的日常生活活动能力评分和运动功能评分均高于治疗前,且治疗组显著高于对照组(P<0.05)。结论:扶阳三焦次第疗法治疗脑梗死能明显改善患者的临床症状,其机制可能与降低血清同型半胱氨酸水平有关。Objective:To observe the clinical effect of Fu Yang"Triple-Jiao Sequential therapy"in the treatment of cerebral infarction.Methods:A total of 60 patients with cerebral infarction admitted to the first affiliated hos pital of Guangxi university of Chinese medicine and the first affiliated hospital of Guangxi medical university from September 2019 to March 2021,which were randomly divided into treatment group(30 patients)and control group(30 patients).The patients in the control group were treated with conventional western medicine,and the patients in the treatment group were treated with traditional Chinese medicine based on the conventional western medicine.Before and after treatment of 4 weeks,the treatment effective rate,the traditional Chinese medicine(TCM)syndrome score,the Activity of Daily Living(ADL)score,the simplified Fugl-Meyer motor function score,neurological function deficit score and serum homocysteine level were compared between the two groups.Results:The effective rate of the treatment group was better than that of the control group,and the difference was statistically significant.After treatment the neurological function score,the TCM syndrome score and the homocysteine level were lower than before treatment,and the scores of treatment group were lower than those of control group(P<0.05).The ADL score,the simplified Fugl-Meyer motor function score were higher than before treatment,and the scores of treatment group were higher than those of control group(P<0.05).Conclusion:Fu Yang"Triple-Jiao Sequential therapy"can significantly improve the clinical symptoms of patients,and the mechanism may be related to the decline of serum homocysteine.
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