感觉神经系统精细中枢投射调控机制的研究进展  

Research progresses of fine-topography of the sensory nervous system

作　　者：何群 王亚春 孙艺萌 曲鹏[1] 杨利敏[1] HE Qun;WANG Ya-chun;SUN Yi-meng;QU Peng;YANG Li-min(Department of Anatomy and Histology and Embryology,School of Medicine,Dalian University,Key Laboratory of Chronic Disease Research,Dalian 116622,China)

机构地区：[1]大连大学医学院解剖与组织胚胎学教研室慢性病研究重点实验室,辽宁大连116622

出　　处：《解剖科学进展》2022年第4期495-498,共4页Progress of Anatomical Sciences

基　　金：国家自然科学基金(31571087)

摘　　要：生物体为了编码外界刺激的部位、产生精确的感觉,不同部位的感觉神经元轴突投射至中枢相应位置并与突触后神经元形成点对点的突触联系,其轴突末梢在中枢相应区域形成立体投射图,这是生物体感觉神经系统感知外界刺激的主要策略。虽然脊椎动物和非脊椎动物中枢投射的形成机制稍有差异,但基本调控机制却是相对保守的。在这里,我们将回顾在果蝇和脊椎动物感觉系统中枢投射中的发现,对生物体感觉神经系统中枢精细投射机制进行综述。The location of external stimulation was encoded to produce unique sensation,the axons of sensory neurons in different parts project to the corresponding positions in the center and form a point-to-point synaptic connection with postsynaptic neurons.The axon ends are formed in related areas of the center.Stereoscopic projection is the main strategy for the organism’s sensory nervous system to perceive external stimuli.Although the formation mechanism of the topographic map of vertebrates and non-vertebrates is somewhat different,the primary regulatory mechanism is conservative.Here,we will review the findings in forming a topographic map of Drosophia and vertebrates’sensory system.

关 键 词：感觉神经元 神经系统 突触联系 外界刺激 中枢 脊椎动物 调控机制 轴突投射 

分 类 号：R338.3[医药卫生—人体生理学]