Valvuloplasty of fetal pulmonary atresia with intact ventricular septum and hypoplastic right heart: Mid-term follow-up results  

作　　者：Gang Luo Shuai Gao Hongxiao Sun Zhixian Ji Dunliang Wang Yue Sun Silin Pan 

机构地区：[1]Heart Center,Women and Children’s Hospital,Qingdao University,Qingdao,266034,PR China [2]Department of Anesthesiology,Women and Children’s Hospital,Qingdao University,Qingdao,266034,PR China [3]Department of Obstetrics,Women and Children’s Hospital,Qingdao University,Qingdao,266034,PR China

出　　处：《Journal of Interventional Medicine》2022年第4期196-199,共4页介入医学杂志（英文）

摘　　要：Objective:This study aimed to analyze and evaluate the results of mid-term follow-up after fetal pulmonary valvuloplasty(FPV)in fetuses with pulmonary atresia with intact ventricular septum(PA/IVS).Methods:From August 31,2018,to May 31,2019,seven fetuses with PA/IVS and hypoplastic right heart were included in this study.All underwent echocardiography by the same specialist and were operated on by the same team.Intervention and echocardiography data were collected,and changes in the associated indices noted during follow-up were analyzed.Results:All seven fetuses successfully underwent FPV.The median gestational age at FPV was 27.54 weeks.The average FPV procedural time was 6 min.Persistent bradycardia requiring treatment occurred in 4/7 procedures.Finally,five pregnancies were successfully delivered,and the other two were aborted.Compared to data before fetal cardiac interventions(FCI),tricuspid valve annulus diameter/mitral valve annulus diameter(TV/MV)and right ventricle diameter/left ventricle diameter(RV/LV)of all fetuses had progressively improved.The maximum tricuspid regurgitation velocity decreased from 4.60 m/s to 3.64 m/s.The average follow-up time was 30.40±2.05 months.During the follow-up period,the diameter of the tricuspid valve ring in five children continued to improve,and the development rate of the tricuspid valve was relatively obvious from 6 months to 1 year after birth.However,the development of the right ventricle after birth was relatively slow.It was discovered that there were individual variations in the development of the right ventricle during follow-up.Conclusion:The findings support the potential for the development of the right ventricle and tricuspid valve in fetuses with PA/IVS who underwent FCI.Development of the right ventricle and tricuspid valve does not occur synchronously during pregnancy.The right ventricle develops rapidly in utero,but the development of tricuspid valve is more apparent after birth than in utero.

关 键 词：Congenital heart disease fetal cardiac intervention fetal pulmonary valvuloplasty hypoplastic right heart syndrome pulmonary atresia with intact septum 

分 类 号：R714.5[医药卫生—妇产科学]