2,4-二羟基苯乙酮应用与合成研究进展  

Advances in the Application and Synthesis of 2,4-Dihydroxyacetophenone

作　　者：王奥 王萌斐 彭效明[1] 杨红瑾 王红平 晁建平[1] WANG Ao;WANG Meng-fei;PENG Xiao-ming;YANG Hong-jin;WANG Hong-ping;CHAO Jian-ping(College of New Materials and Chemical Engineering,Beijing Institute of Petrochemical Technology,Beijing 102617,China;Beijing Tianhong Tianda Medicine Co.,Ltd.,Beijing 102629,China)

机构地区：[1]北京石油化工学院新材料与化工学院,北京102617 [2]北京天虹天达医药科技股份有限公司,北京102629

出　　处：《精细化工中间体》2022年第5期6-11,共6页Fine Chemical Intermediates

基　　金：国家自然科学基金资助项目(81703453);北京石油化工学院校内学科平台建设项目(2019XK006)

摘　　要：2,4-二羟基苯乙酮是一种重要的精细化工中间体,已广泛应用在药物合成和检测等行业。以间苯二酚为原料,基于反应催化剂,对2,4-二羟基苯乙酮的合成路线进行了综述,并对其进一步研究和发展方向进行了展望。2,4-Dihydroxyacetophenone is an important fine chemical intermediate that has been applied in drug synthesis,assay and other industrial areas.The synthetic routes of 2,4-dihydroxyacetophenone which using resorcinol as the raw material were reviewed from the perspective of this reaction catalyst,and the direction of its further research and development were reported.

关 键 词：2 4-二羟基苯乙酮 Friedel-Crafts酰化反应 合成 催化剂 

分 类 号：TQ244.2[化学工程—有机化工]