延龄草皂苷类成分及其药理活性、资源保育的研究进展  

Research progress on saponins from Trillium tschonoskii and their pharmacological activities and resource conservation

作　　者：林泉 秦双双[2,3] 韦坤华[2,3] 梁莹[2,3] 韦范[2,3] 缪剑华 LIN Quan;QIN Shuangshuang;WEI Kunhua;LIANG Ying;WEI Fan;MIAO Jianhua(College of pharmacy,Guangxi University of Chinese Medicine,Nanning 530200,Guangxi,China;Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement,Guangxi Botanical Garden of Medicinal Plants,Nanning 530023,Guangxi,China;Guangxi Engineering Research Center of TCM Resource Intelligent Creation,Guangxi Botanical Garden of Medicinal Plants,Nanning 530023,Guangxi,China)

机构地区：[1]广西中医药大学药学院,广西南宁530200 [2]广西壮族自治区药用植物园,广西药用资源保护与遗传改良重点实验室,广西南宁530023 [3]广西壮族自治区药用植物园,广西壮族自治区中药资源智慧创制工程研究中心,广西南宁530023

出　　处：《生物资源》2022年第6期525-539,共15页Biotic Resources

基　　金：国家自然科学基金(82160723);广西自然科学基金(2020GXNSFBA159018、2021GXNSFAA196054);珍稀濒危药用资源保护与可持续利用关键技术研发(桂科AD22080012)

摘　　要：延龄草是土家族四大名药之一,具有活血祛瘀、镇静安神、治疗跌打损伤等功效,现代药理研究表明其在改善阿尔茨海默症等中枢神经退化性疾病方面具有一定疗效。由于早年的大量采挖及现代保育工作尚未完善,延龄草资源稀缺,已被列为国家三级珍稀濒危保护植物。本文归纳了延龄草皂苷类成分及其结构分类、药理活性以及资源保育方面的研究进展,剖析了目前延龄草资源发展中亟待解决的问题,旨在为延龄草资源的可持续利用和产业发展提供基础和依据。Trillium tschonoskii is one of the four famous medicines of Tujia nationality,which has the effects of promoting blood circulation and removing blood stasis,calming nerves and treating traumatic injuries.Modern pharmacological studies show that it has certain curative effect in improving central nervous degenerative diseases such as Alzheimer’s disease.Due to the massive excavation in the early years and the imperfect modern conservation work,the resource of T.tschonoskii is scarce and has been listed as the national third level rare and endangered plant.In this paper,the research progresses of saponins and their structural classification,pharmacological activity and resource conservation in T.tschonoskii are summarized,and the problems to be solved in the development of T.tschonoskii resources are analyzed,in order to provide the basis and basis for the sustainable utilization and industrial development of T.tschonoskii resources.

关 键 词：延龄草 皂苷类成分 药理活性 资源保育 

分 类 号：R282.2[医药卫生—中药学]