胰岛素泵持续皮下输注与多次胰岛素皮下注射临床治疗效果比较  

The Comparative Study of the Clinic Effect between the Insulin Pump and the Multiple Daily Injection

作　　者：李敏 贾银虎[1] LI Min;JIA Yin-hu(Department of adultInternal Medicine,Hebei children's hospital,Shijiazhuang Hebei 050000)

机构地区：[1]河北省儿童医院成人内科,河北石家庄050000

出　　处：《世界最新医学信息文摘》2021年第6期209-210,共2页World Latest Medicine Information Electronic Version

基　　金：河北省卫生健康委科研基金项目(20190826)。

摘　　要：目的比较短期胰岛素泵持续皮下输注胰岛素与多次皮下注射胰岛素治疗T2DM的疗效.方法选择住院需要强化胰岛素治疗的2型糖尿病患者共120例,根据患者意愿,分为胰岛素泵治疗组(CSⅡ组)及多次皮下注射胰岛素组(MSⅡ组);比较两组患者的血糖达标时间、低血糖发生率以及三个月时糖化血红蛋白水平.结果治疗后两组患者之间的血糖达标时间、低血糖发生率差异有统计学意义(P<0.05);而三个月时糖化血红蛋白水平差异无统计学意义(P>0.05).结论两种注射方法均能有效降低血糖,但应用胰岛素泵可更快使血糖达标,且低血糖发生率低,住院时间短,其临床应用效果优于多次皮下注射方式.Objective To compare the efficacy and adverse effects between insulin pump and multiple daily injection in T2DM patients.Methods The 120 T2DM patients who needed to control the blood glucose were divided into two groups:the insulin pump and themultiple daily injection,the time to achieve the glycemic control,incidence of hypoglycemic andthe HbA1c of the third month were studied for comparison.Results There were statistical differences in the time to achieve the glycemic control and incidence of hypoglycemic between the two groups(P<0.05);There were no statistical differences in theHbA1c of the third month between the two groups(P>0.05).Conclusion The two different treatments all can lower the blood glucose,but insulin pump short-term intensive treatment can smoothly and effectively control theblood glucose,the glucose-lowering effect is better than that of insulin 4 times daily injection.

关 键 词：胰岛素泵 持续皮下胰岛素输注 胰岛素强化治疗 糖尿病 2型 

分 类 号：R587.1[医药卫生—内分泌]