消化道肿瘤化疗辅以还原型谷光苷肽治疗的临床分析  

Clinical Analysis of Chemotherapy Combined with Reduced Glutathione for Gastrointestinal Cancer

作　　者：田雪 TIAN Xue(Jilin Guowen Hospital,Gongzhuling Jilin 136100)

机构地区：[1]吉林国文医院,吉林公主岭136100

出　　处：《世界最新医学信息文摘》2020年第2期20-21,共2页World Latest Medicine Information Electronic Version

摘　　要：目的探讨消化道肿瘤化疗辅以还原型谷胱甘肽治疗的临床效果.方法随机抽取本院2017年5月至2019年6月时间段内诊疗的110例消化道肿瘤患者,划分为A组55例、B组55例.即A组采用化疗+奥美拉唑治疗模式,B组采用化疗+还原型谷胱甘肽治疗模式,对比患者总有效率、症状改善及生活质量评分、不良反应总发生率.结果A组总有效率为85.45%,B组为98.18%,各数据间比较有意义(P<0.05).B组症状改善及生活质量评分较优于A组,各数据间比较有意义(P<0.05).A组不良反应总发生率为18.17%,B组为5.45%,各数据间比较有意义(P<0.05).结论于消化道肿瘤患者中,以化疗为基础联合还原型谷胱甘肽治疗模式,既可增强患者总有效率,还可改善症状表现和生活质量,预防或减少不良反应,应加大推广力度.Objective to explore clinical effect of chemotherapy combined with reduced glutathione for gastrointestinal cancer.Methods choose 110 cases digestive gastrointestinal cancer patients from May 2017 to June 2019 in our hospital.Divide them into group A(55 cases)and group B(55 cases)randomly.Group A was treated with chemotherapy plus omeprazole,while group B with chemotherapy plus reduced glutathione.Compare total effective rate,symptom improvement,life quality scores and total adverse reactions incidence of two groups.Results total effective rate in group A was 85.45%and 98.18%in group B,data comparison showed significance,(P<0.05).Symptom improvement and life quality scores of group B were better than group A,data comparison showed significance,(P<0.05).Total adverse reactions incidence was 18.17%in group A and 5.45%in group B,data comparison showed significance(P<0.05).Conclusion chemotherapy combined with reduced glutathione treatment mode can enhance total effective rate of gastrointestinal cancer patients,improve symptoms and life quality,prevent or reduce adverse reactions,which is worthy of great promotion.

关 键 词：消化道肿瘤 还原型谷胱甘肽 奥美拉唑 化疗 临床效果 

分 类 号：R459.5[医药卫生—治疗学]