复方米非司酮配伍利凡诺尔在中孕引产中的临床应用  

Clinical Application of Compound Mifepristone Combined with Rivanolol in the Induction of Labor

作　　者：张胜英[1] 耿昕[1] 张丽娜[1] ZHANG Sheng-ying;GENG Xin;ZHANG Li-na(Obstetrics and Gynecology Department,Suzhou Wuzhong People's Hospital of Jiangsu Province,Suzhou 215128,Jiangsu,China)

机构地区：[1]江苏省苏州市吴中人民医院妇产科,江苏苏州215128

出　　处：《医学信息》2017年第8期76-77,共2页Journal of Medical Information

摘　　要：目的 观察复方米非司酮配伍利凡诺尔在中期妊娠引产中的临床应用效果.方法 选择我院2013年1月~2016年1月收治妊娠16~28 w自愿要求引产的病例102例,排除利凡诺尔应用禁忌症,随机分为两组.对照组51例为利凡诺尔100 mg经腹羊膜腔内注射,观察组51例经羊膜腔内注入利凡诺尔100 mg后加服复方米非司酮120 mg(30 mg,12h 1次,共4次),观察两组宫缩出现时间、胎儿娩出时间、患者疼痛评分、出血量及清宫时宫内残留量、引产成功率等方面差异.结果 观察组宫缩出现时间早、胎儿排出时间短,疼痛评分低,宫腔残留量少,明显优于对照组,而出血量及成功率,副反应等方面无明显差异.结论复方米非司酮配伍利凡诺尔用于中期妊娠引产,较利凡诺尔单一用药更安全有效.Objective To observe the effect of compound mifepristone combined with Woolley van Knoll in the mid trimester of pregnancy induced labor in the clinical application.Methods In our hospital during January 2013~2016 January 16~28 w pregnancy 102 cases of voluntary labor requirements,exclude the application of rivanol contraindication were randomly divided into two groups.The control group of 51 cases of rivanol 100 mg transabdominal amniotic injection.The observation group 51 cases amniotic injection of rivanol 100 mg after taking compound mifepristone 120 mg(30 mg,1 time,12h,4 times),observe two groups of uterine contraction time,delivery time,pain score,bleeding and avoid intrauterine residue differences.Results The success rate of the observation group contractions occurred earlier,fetal discharge time is short,low pain scores,intrauterine residue less,significantly better than the control group,and the amount of bleeding and the success rate,no significant difference in adverse reaction and so on.Conclusion Compound mifepristone with Woolley van Noel ketone for mid pregnancy abortion,compared with rivanol monotherapy is more safe and effective.

关 键 词：复方米非司酮 利凡诺尔 中孕妊娠 引产 

分 类 号：R71[医药卫生—妇产科学]