咳嗽变异性哮喘患者吸入性和食物性变应原检测分析  

Detection and Analysis of Inhalant&Food Allergen in Patients with Cough Variant Asthma

作　　者：单咏梅[1] 陆震宇 沈英[1] 胡江 李冬[1] SHAN Yong-mei;LU Zhen-yu;SHEN Ying;HU Jiang;LI Dong(Department of Clinical Laboratory,Tongji Hospital Affiliated to Tongji University,Shanghai 200065,China;Department of Clinical Laboratory,Shanghai Liqun Hospital,Shanghai 200333,China)

机构地区：[1]同济大学附属同济医院检验科,上海200065 [2]上海市利群医院检验科,上海200333

出　　处：《医学信息（医学与计算机应用）》2016年第35期34-35,共2页Medical Information

摘　　要：目的 研究吸入性和食物性变应原在咳嗽变异性哮喘患者中的检出率,为临床的诊断和治疗提供依据.方法 对145例咳嗽变异性哮喘CVA患者,采用欧蒙印迹法检测吸入性和食物性变应原特异性IgE抗体,以非CVA组112例作为对照.结果 CVA组吸入性和食物性变应原阳性率分别为70.34%和21.38%,相比非CVA组的16.07%和5.54%,二者比较差异有明显的统计学意义(<0.01).吸入性变应原以尘螨和蟑螂为主,食物性变应原以虾和蟹为主.结论 CVA患者以吸入性变应原感染为主,但存在吸入性和食物性变应原同时被检出现象,食物性变应原检测在预测过敏过程和预防CVA发生中具有潜在的应用价值.Objective To study the detection rate of inhaled&food allergen in patients with cough variant asthma,thus to provide basic datas for clinical diagnosis and treatment.Methods 145 cases of the patients with CVA,Euroimmun imprinting method was used to detect specific IgE antibody for inhaled&food allergens,112 patients with not-CVA group was set up as the contrast.Results Compared with not-CVA group's 16.07%and 5.54%,the positive rate of inhalant allergen of the patients with CVA was 70.34%and the positive rate of food allergen was 21.38%,and there was significant statistical difference between two groups(<0.01).Inhalant allergens in patients with CVA were given priority to dust mites and cockroaches,food allergens were given priority to shrimp and crab.Conclusion The patients with CVA were given priority to inhalant allergen infection.Food allergies in patients with CVA frequently coexist with inhaled allergies,and food allergens detection in predicting allergic process and the prevention of CVA occurs has potential applications.

关 键 词：咳嗽变异性哮喘 吸入性和食物性变应原 检测分析 

分 类 号：R5[医药卫生—内科学]