Relationship of Cystatin-C with coronary artery disease in the elderly patients with diabetes  

作　　者：Qinxue Li Biao Ge Ruijing Yan Yinlong Bai Yan Liu 

机构地区：[1]Department of Geriatrics,The Third Affiliated Hospital of Inner Mongolia Medical College,Baotou,China

出　　处：《Discussion of Clinical Cases》2017年第3期1-3,共3页临床病例讨论杂志（英文版）

摘　　要：Objective: To study the relationship between Cystatin C (Cys-C) level and the development of coronary heart disease in elderly patients with type 2 diabetes mellitus (T2DM). Methods: 120 cases of elderly diabetic patients were involved in this study from October 2013 to November 2015 in Depart-ment of Endocrinology and Cardiology. All patients underwent the detection of routine flash dual-source coronary computed tomography angioplasty (CCTA), Cys-C, hemoglobin A1c (HbA1c). According to the difference of CCTA results, the patients were divided into DM1 group (with normal coronary CTA), DM2 group (with a coronary artery stenosis rate < 50%), DM3 group (with a coronary artery stenosis rate of 50%-74%) and DM4 group (with a coronary artery stenosis rate of ≥ 75%). The levels of Cys-C and HbA1c were compared in the four groups. Results: The blood levels of Cys-C and HbA1c showed significant differences between DM1, DM2, DM3 and DM4 group (p <.05). The age, heart rate, blood pressure showed no statistical differences between the groups. The level of Cys-C was positively correlated with HbA1c. Conclusions: The blood level of Cys-C in the elderly patients with T2DM increased with the increase of the degree of coronary artery stenosis. Blood Cys-C may be used as an early predictor of coronary artery lesions in elderly patients with T2DM.

关 键 词：Type 2 DIABETES CORONARY HEART disease CYSTATIN C Flash dual-source CT 

分 类 号：R5[医药卫生—内科学]