Non-invasive estimation of pulmonary hypertension and clinical deterioration risk in pediatric congenital heart disease:Development and validation of predictive tools  

作　　者：Ting Wang Dansha Zhou Yuqin Chen Suhua Kuang Yue Xing Qijian Yi Zhengxia Pan Weibin Xu Jiao Rao Yunqi Liu Guoliang Lu Ziying Lin Xiang Li Yi Xie Yulong Wu Peng An Xiaoxiao Deng Jiayue He Jiayi Xie Chenxi Li Gang Geng Daiyin Tian Enmei Liu Jingsi Huang Zhou Fu Jian Wang 

机构地区：[1]Department of Respiratory,Chongqing Higher Institution Engineering Research Center of Children’s Medical Big Data Intelligent Application,National Clinical Research Center for Child Health and Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,Children’s Hospital of Chongqing Medical University,Chongqing 400014,China [2]State Key Laboratory of Respiratory Diseases,National Center for Respiratory Medicine,Guangdong Key Laboratory of Vascular Diseases,National Clinical Research Center for Respiratory Diseases,Guangzhou Institute of Respiratory Health,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou Medical University,Guangzhou,Guangdong 510120,China [3]Department of Cardiac Surgery,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou Medical University,Guangzhou,Guangdong 510120,China [4]Department of Cardiovascular Medicine Children’s Hospital of Chongqing Medical University,National Clinical Research Center for Child Health and Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,Children’s Hospital of Chongqing Medical University,Chongqing 400014,China [5]Department of Thoracic and Cardiac Surgery Children’s Hospital of Chongqing Medical University,National Clinical Research Center for Child Health and Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,Children’s Hospital of Chongqing Medical University,Chongqing 400014,China [6]Department of Cardiac Center of Guangdong Women and Children Hospital Guangzhou,Guangzhou,Guangdong 511400,China [7]Department of Guangzhou Laboratory,Guangzhou International Bio Island,Guangzhou,Guangdong 510005,China

出　　处：《Chinese Medical Journal》2024年第11期1384-1386,共3页中华医学杂志（英文版）

基　　金：National Natural Science Foundation of China(Nos.82000034,82120108001,and 82170069);Chongqing Postdoctoral International Exchange Training Program(No.2021JLPY001);National Clinical Medical Research Center(No.NCRC-2022-GP-08);Guangdong Department of Science and Technology(No.2022A0505030017);Basic Science and Application of Guangzhou Science and Technology Plan(No.202201010069)

摘　　要：To the Editor:Owing to the heterogeneity of congenital heart disease-associated pulmonary hypertension(CHDPH)disease and the development of the pulmonary vascular system in pediatric patients,the management of CHD-PH in children is signicantly different from that in adults.[1]Early identication and intervention of CHD-PH are of great signicance for disease management in children with CHD,and non-invasive,accurate clinical tools are urgently needed to predict PH risk in children with CHD.However,the applicability of the current risk-scoring system to pediatric CHD-PH remains unclear.Furthermore,there are presently no user-friendly,non-invasive online tools available for predicting CHD-PH,and there is a scarcity of related studies in Asian populations.This study aimed to develop and validate the prediction tools for estimating the risk of pulmonary hypertension and clinical deterioration in children with congenital heart disease.

关 键 词：PEDIATRIC CONGENITAL HYPERTENSION 

分 类 号：R725.5[医药卫生—儿科]