脉搏血氧饱和度/吸入氧浓度与动脉氧分压/吸入氧浓度诊断急性呼吸窘迫综合征:孰优孰劣?  

Pulse oximetric saturation/fraction of inspired oxygen and partial pressure of oxygen/fraction of inspired oxygen in diagnosing acute respiratory distress syndrome:which is better?

作　　者：孟祥林[1] 熊雅欣 赵鸣雁[1] Meng Xianglin;Xiong Yaxin;Zhao Mingyan(Department of Critical Care Medicine,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院重症医学科,哈尔滨150001

出　　处：《中华医学杂志》2024年第15期1221-1224,共4页National Medical Journal of China

基　　金：国家自然科学基金(82172164);黑龙江省重点研发计划(GA21C011,JD22C005)

摘　　要：急性呼吸窘迫综合征(ARDS)以低氧血症为主要特征,其发病率高、病死率高、医疗花费大,给患者和社会带来巨大负担。目前针对ARDS缺乏有效的治疗药物,早期诊断和及时干预仍然是ARDS救治成功的关键。动脉氧分压/吸入氧浓度(PaO_(2)/FiO_(2),P/F)一直被用作评估患者低氧血症和病情严重程度的重要指标。虽然其相对准确,但对操作技术水平和医疗设备条件需要较高要求,这些因素均限制了ARDS诊疗在医疗水平欠发达地区的开展实施,也造成了ARDS的漏诊漏治。脉搏血氧饱和度/吸入氧浓度(SpO_(2)/FiO_(2),S/F)因其简便、无创及可持续性监测的特点,越来越受到人们的关注。本文旨在比较S/F与P/F在ARDS诊断过程中的相关性、准确性和临床实用性,以便能够提出更加快速、准确地评估ARDS患者氧合情况的诊断指标。Acute Respiratory Distress Syndrome(ARDS)is distinguished by hypoxemia,contributing to heightened morbidity,elevated mortality rates,and substantial healthcare expenses,thereby imposing a significant burden on patients and society.Presently,effective treatments for ARDS are lacking,emphasizing the pivotal role of early diagnosis and timely intervention in its successful management.The partial pressure of oxygen/fraction of inspired oxygen(PaO_(2)/FiO_(2),P/F)has traditionally served as a crucial metric for assessing patient hypoxemia and disease severity.While relatively accurate,its reliance on advanced technical expertise and specific medical equipment conditions constrains its implementation in areas with underdeveloped medical standards,resulting in missed diagnoses and treatments for ARDS patients.Conversely,the Pulse oximetric saturation/fraction of inspired oxygen(SpO_(2)/FiO_(2),S/F)has garnered increasing attention owing to its straightforward,non-invasive,and sustainable monitoring attributes.This article seeks to meticulously compare the correlation,accuracy,and clinical feasibility of S/F with P/F in ARDS diagnosis,so as to propose diagnostic indicators for more quickly and accurately assessing the oxygenation status of ARDS patients.

关 键 词：呼吸窘迫综合征 成人 诊断 动脉氧分压/吸入氧浓度 血氧饱和度/吸入氧浓度 

分 类 号：R563.8[医药卫生—呼吸系统]