体外二氧化碳清除在急性呼吸窘迫综合征救治中的应用价值  

Clinical value of the implication of extracorporeal carbon dioxide removal in patients with acute respiratory distress syndrome

作　　者：徐永昊[1] 刘宜坤 席寅[1] 王亚 黎毅敏[1] Xu Yonghao;Liu Yikun;Xi Yin;Wang Ya;Li Yimin(Department of Critical Care Medicine,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou Institute of Respiratory and Health,National Center for Respiratory Medicine,State Key Laboratory of Respiratory Disease,Guangzhou 510120,China)

机构地区：[1]广州医科大学附属第一医院重症医学科,广州呼吸健康研究院,国家呼吸医学中心,呼吸疾病全国重点实验室,广州510120

出　　处：《中华医学杂志》2024年第15期1242-1246,共5页National Medical Journal of China

基　　金：国家自然科学基金(82241003);广州医科大学学科建设项目(02-445-2301011XM);广东省医学科研基金(A2023440)

摘　　要：体外二氧化碳清除(ECCO_(2)R)是一种基于肺外气体交换的呼吸辅助体外生命支持技术,可以有效清除机体代谢生成的二氧化碳,以降低患者通气需求和呼吸机支持水平。随着体外生命支持相关技术的改进和临床经验的增多,研究提示ECCO_(2)R的临床应用具有潜在价值。本文阐述了ECCO_(2)R使用的原理、救治急性呼吸窘迫综合征(ARDS)的相关适应证、研究成果、存在的问题以及研究方向,以期为ARDS患者的救治提供更多参考。Extracorporeal carbon dioxide removal(ECCO_(2)R)is a respiratory support technique based on extra-pulmonary gas exchange,which can effectively remove carbon dioxide generated in-vivo,reducing the requirements of respiratory support from mechanical ventilation.With improvements in extracorporeal life support technologies and increasing clinical experience,ECCO_(2)R has potential value in clinical application with acute respiratory distress syndrome(ARDS).This review article discusses the principles of ECCO_(2)R,its relevant indications for ARDS,clinical evidence,existing issues,and future directions,aiming to provide more references for the application in ARDS.

关 键 词：呼吸窘迫综合征 成人 体外二氧化碳清除 适应证 并发症 

分 类 号：R563.8[医药卫生—呼吸系统]