地方性氟中毒致机体损伤的研究进展  

Research progress of body damage caused by endemic fluorosis

作　　者：赵凡 郭志伟 Zhao Fan;Guo Zhiwei(School of Public Health,Inner Mongolia Medical University,Hohhot 010110,China;Business Management Department,the Inner Mongolia Autonomous Regional Comprehensive Center for Disease Control and Prevention,Hohhot 010080,China)

机构地区：[1]内蒙古医科大学公共卫生学院,呼和浩特010110 [2]内蒙古自治区综合疾病预防控制中心业务处,呼和浩特010080

出　　处：《中华地方病学杂志》2024年第1期71-76,共6页Chinese Journal of Endemiology

基　　金：内蒙古自治区科技计划项目(2021GG0383)

摘　　要：地方性氟中毒是指生活在由自然或人为污染所致高氟环境中的居民,因体内摄入过量氟化物而引起的一种地方性疾病。氟斑牙、氟骨症是地方性氟中毒较常见的症状;此外,长期氟暴露还可引起神经系统、心血管系统、泌尿系统等多个系统的损伤,最终导致全身多器官的慢性病变和功能障碍。目前,地方性氟中毒仍是我国乃至世界的严重公共卫生问题之一。故本文从骨相和非骨相系统两方面就地方性氟中毒对人群机体损伤的研究进展进行综述,以期为今后地方性氟中毒的持续防控提供参考依据。Endemic fluorosis refers to an endemic disease caused by excessive intake of fluoride in the body of residents living in high fluoride environment due to natural or man-made pollution.Dental fluorosis and bone fluorosis are common symptoms of endemic fluorosis.In addition,long-term exposure to fluorine can cause damage to multiple systems such as the central nervous system,cardiovascular system,urinary system,ultimately leading to chronic lesions and functional impairments of multiple organs throughout the body.At present,endemic fluorosis remains one of the serious public health problems in China and even the world.Therefore,this article reviews the research progress on the damage of endemic fluorosis to the human body from both bone and non-bone systems,in order to provide reference for the continuous prevention and control of endemic fluorosis in the future.

关 键 词：氟 机体损伤 骨相系统 非骨相系统 

分 类 号：R599.1[医药卫生—内科学]