Efficacy of intrauterine balloon stent or oral estrogen on prevention of adhesion after transcervical resection of septum in septate uterus:Study protocol for a randomized controlled multicenter study in China  

作　　者：Shan Deng Zichen Zhao Limin Feng Xiaowu Huang Sumin Wang Xiang Xue Lei Yan Baorong Ma Lijuan Hao Xueying Li Lihua Yang Lan Zhu 

机构地区：[1]Department of Obstetrics and Gynecology,National Clinical Research Center for Obstetric&Gynecologic Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China [2]Department of Obstetrics and Gynecology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China [3]Department of Hysteroscopic Center,Fuxing Hospital,Capital Medical University,Beijing 100038,China [4]Nanjing Maternity and Child Health Care Hospital,Jiangsu Province 210004,China [5]The Second Affiliated Hospital of Xi’an Jiaotong University,Shanxi Province 710004,China [6]Center for Reproductive Medicine,Cheeloo College of Medicine,Shandong University,Shandong Province 250012,China [7]Tianjin Central Hospital of Obstetrics and Gynecology,Tianjin 300199,China [8]Chongqing Health Center for Women and Children,Chongqing 401147,China [9]Hunan Provincial Maternal and Child Health Care Hospital,Hunan Province 410008,China [10]Tangshan Maternal and Child Health Care Hospital,Hebei Province 063000,China

出　　处：《Chinese Medical Journal》2023年第24期3016-3018,共3页中华医学杂志（英文版）

基　　金：supported by a grant from the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(NO.2020-PT320-003)

摘　　要：To the Editor:The septate uterus is the most common uterine anomaly and is associated with an increased risk of adverse reproductive outcomes.Transcervical resection of septum(TCRS)is widely performed in patients with adverse reproductive outcomes.The incidence of de novo intrauterine adhesions(IUAs)after TCRS is approximately 5%to 25%.[1]Various anti-adhesion methods are widely used in the clinical management of patients with septate uteri,including intrauterine devices,Foley balloons,estrogen,antibiotics,and hyaluronic acid gel.However,insufficient evidence supports or opposes any of these methods(Level C),[2]lacking high-grade evidence.

关 键 词：PREVENTION SEPTUM AFTER 

分 类 号：R713.4[医药卫生—妇产科学]