Antiviral effects of artemisinin and its derivatives  

作　　者：Hao Liu Zhen Li Yang Zhang Lin Jia Miaotian Cai Rui Wang Caiping Guo 

机构地区：[1]Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China [2]Beijing Key Laboratory for HIV/AIDS Research,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China [3]Department of Dermatology,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China [4]Department of Respiratory and Critical Care Medicine,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China

出　　处：《Chinese Medical Journal》2023年第24期2993-2995,共3页中华医学杂志（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(Nos.82072271 and 82072294);the Beijing Natural Science Foundation(No.7222091);the Peak Talent Program of Beijing Hospital Authority(No.DFL20191701);the Beijing Hospitals Authority Innovation Studio of Young Staff Funding Support(No.202137);the High-level Public Health Technical Personnel Construction Project,and the Beijing Key Laboratory for HIV/AIDS Research(No.BZ0089)

摘　　要：To the Editor:Artemisinin is a sesquiterpene lactone compound with a peroxide bridge structure,which is extracted and isolated from the medicinal plant,Artemisia annua L.Existing studies have revealed a broad spectrum of potential applications of artemisinin compounds in antitumor,immune regulation,osteoporosis prevention,antibacterial and antiviral roles over the years,making it effective against a range of other diseases,which broadened the clinical applications of artemisinin.Herein,we update the current knowledge of the antiviral activities of artemisinin and its derivatives against diverse viruses such as Coronaviridae,Herpesviridae,and Flaviviridae.Studies on the antiviral effect of artemisinin-type compounds can provide new ideas to fight the emerging viral disease for which no effective antiviral drugs are available.

关 键 词：DERIVATIVES SPECTRUM PREVENTION 

分 类 号：R285[医药卫生—中药学]