Post-tuberculosis lung disease and chronic obstructive pulmonary disease  

作　　者：Xiaoyan Gai Brian Allwood Yongchang Sun 

机构地区：[1]Department of Respiratory and Critical Care Medicine,Peking University Third Hospital,Center for Chronic Airway Diseases,Peking University Health Science Center,Peking University,Beijing 100191,China [2]Division of Pulmonology,Department of Medicine,Stellenbosch University&Tygerberg Academic Hospital,Cape Town,South Africa

出　　处：《Chinese Medical Journal》2023年第16期1923-1928,共6页中华医学杂志（英文版）

基　　金：supported by grants from the National Natural Science Foundation(Nos.81400041 and 8217010845);the Capital’s Funds for Health Improvement and Research(No.2022-2G-40910);the Key Clinical Projects of Peking University Third Hospital(No.BYSYZD2022014)

摘　　要：The burden of chronic airway diseases,including chronic obstructive pulmonary disease(COPD),continues to increase,especially in low-and middle-income countries.Post-tuberculosis lung disease(PTLD)is characterized by chronic lung changes after the"cure"of pulmonary tuberculosis(TB),which may be associated with the pathogenesis of COPD.However,data on its prevalence,clinical manifestations,computed tomography features,patterns of lung function impairment,and influencing factors are limited.The pathogenic mechanisms underlying PTLD remain to be elucidated.This review summarizes the recent advances in PTLD and TB-associated COPD.Research is urgently needed both for the prevention and management of PTLD.

关 键 词：Tuberculosis Post-tuberculosis lung disease Chronic obstructive pulmonary disease 

分 类 号：R563[医药卫生—呼吸系统] R521[医药卫生—内科学]