Use of edaravone to decrease perioperative neurocognitive disorders in elderly patients with hip replacement  

作　　者：Yujing Yuan Liujiazi Shao Xin Luo Fushan Xue 

机构地区：[1]Department of Anesthesiology,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China.

出　　处：《Chinese Medical Journal》2023年第5期629-630,共2页中华医学杂志（英文版）

摘　　要：To the Editor:By a randomized controlled trial,Xi et at[1]assessed the effects of edaravone on the development of postoperative delirium(POD)and perioperative neurocognitive disorders(PND)in elderly patients with hip replacement and showed that edaravone significantly decreased the incidence of POD within 7 days after surgery and the incidences ofPNDat 1 and 12months after surgery.Given that both PODand PND are common complications after hip surgery in elderly patients and have been significantly associated with postoperative death,hospital-acquired complications,persistent cognitive impairments,poor postoperative functional recovery,prolonged duration of hospital stay,and increased healthcare costs,[2,3]their findings have potential implications.However,we noted several issues of this study on which we would like to invite authors’comments.

关 键 词：patients SURGERY DISORDERS 

分 类 号：R687.4[医药卫生—骨科学] R749.1[医药卫生—外科学]