Effect of Enalapril and Levoamlodipine on Essential Hypertension  

作　　者：HUXu 

机构地区：[1]Xiangzhu Central Health Center of Yongkang City, Jinhua Zhejiang 321313, China

出　　处：《外文科技期刊数据库(文摘版)医药卫生》2022年第9期139-142,共4页

摘　　要：Objective: to study the clinical effect of enalapril plus levoamlodipine benzene acid for treatment in essential hypertension. Methods: 60 eligible patients for the study were treated with enalapril, 30 of whom were treated with levoamlodipine. Compare the treatment effect of patients and the difference in the dynamic blood pressure level and medication-related adverse reactions between the two groups before medication, 1 month of medication and 3 months of medication. Results: in the control group, there were 9 significantly effective patients (30%), 18 effective patients (60%), 3 ineffective patients (30%), and the total response rate of 90%. In the control group, there were 18 significantly effective patients (60%), 11 effective patients (33.33%), 1 ineffective patient (3.33%), and the total effective rate of 96.67% (p <0.05);the 24hSBP and 24hDBP in the observation group at 1 month and 3 months were significantly lower than that in the control group;four cases of adverse reactions occurred in the control group. Among them, one case of body edema, one case of facial flushing, two cases of headache and fatigue, the overall incidence of adverse reactions was 10%;a total of 4 cases of adverse reactions occurred in the observation group. Among them, 1 case of body edema, 1 case of facial flushing, 2 cases of headache and fatigue were 14%. The differences between the groups were not statistically significant (p> 0.05). After treatment with different treatments, the difference between sleep quality and life quality was insignificant, and P> 0.05, there was no significant difference after treatment, and P <0.05 was comparable. Conclusion: primary hypertension can be better controlled under the combination of the drug, without significantly aggravating the adverse effects, which is of in-depth research value.

关 键 词：essential hypertension combination medication ambulatory blood pressure level 

分 类 号：R972+.4[医药卫生—药品]