住院老年人药疹73例临床分析  

Clinical Analysis of 73 Elder Inpatients with Drug Eruption

作　　者：郑云燕[1] 康定华[1] 李晓东[2] 

机构地区：[1]江苏省常州市第一人民医院皮肤科,江苏常州213003 [2]南京医科大学第一临床医学院,江苏南京210000

出　　处：《岭南皮肤性病科杂志》2007年第6期348-350,共3页Southern China Journal of Dermato-Venereology

摘　　要：目的:分析住院老年人药疹的致敏药物、皮疹类型及治疗。方法:对我院2003年1月-2007年7月期间诊断的73例住院老年人药疹患者进行回顾性分析。结果:老年人基础病多,用药复杂,19例患者致敏药物难以确定。引起或可能引起药疹的药物有14类,以抗生素居首,最常见为青霉素类、头孢菌素类药。重症药疹主要致敏药物为抗痛风药及抗癫痫药。皮疹类型以麻疹样或猩红热样发疹型占首位,其次为多形红斑型。结论:临床医师用药时,应详细询问病史,严格掌握用药指征,并注意避免交叉敏感和多元敏感的发生。Objective:To explore the causative agents and the clinical features of drug erup- tions among the elder inpatients and their treatment.Methods:The clinical data of 73 elder inpa- tients were collected from January,2003 to July,2007 and retrospectively analyzed.Results:Elder inpatients have many underlying diseases and their medications are complicated.The causative a- gents of 19 patients are hard to determine.There are 14 possible agents and among which,antimi- crobials rank top.The most common causative agents are penicillin and cephalosporin.The major causative agents of serious drug eruption are anti-arthrolithiasis drugs and anti-epilepsia drugs. The dominant types of drug eruptions are morbilliform and scarlatiniform eruptions,followed by er- ythema multiform drug eruption.Conclusion:Clinical physicians should inquire history carefully, only use medications when indicated and avoid crossing allergy and multiple allergy when prescribe medications.

关 键 词：药疹 老年人 致敏药物 临床分析 

分 类 号：R758.25[医药卫生—皮肤病学与性病学]