老年体检中不同尿蛋白测定方法的比较  

Observation and comparison of urinary protein detection with different ways in the health examination of the elderly

作　　者：王顺[1] 徐升强[1] 

机构地区：[1]武汉市第一医院检验科,湖北武汉430022

出　　处：《中国实验诊断学》2007年第11期1528-1530,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的在老年体检中用不同方法进行尿蛋白测定并对结果进行观察比较。方法使用常规尿蛋白测定试纸法、尿微量白蛋白干化学试带、尿液总蛋白测定及免疫比浊法尿微量白蛋白定量测定的方法对100例老年体检尿液标本及100例青年体检尿液标本进行检测。结果200例标本常规尿蛋白测试均为阴性,免疫比浊法测定、尿微量白蛋白干化学试带法及尿液总蛋白浓度测定敏感度高,与免疫比浊法相比,尿微量白蛋白干化学试带法测定的敏感性为94.7%,特异性为86.4%。干化学试带法测定阳性标本的尿总蛋白浓度与阴性标本相比,结果有极显著性差异(P<0.01)。结论在老年体检中,常规的尿蛋白测定意义不大,干化学试带法检测尿微量白蛋白是一种简便可靠的方法,有一定的应用价值。Objective To observe and compare the urinary protein detection with different ways in the health examination of the elderly.Methods One hundred urine specimens of elderly and one hundred urine specimens of young people were detected by conventional protein in urine dipstick and microalbumin test strips,at the same time,the concentration of urine total protein were measured by chemical turbidimetry and the concentration of the microalbumin were measured by immune turbidimetry.Results 200 cases routine tests were negative,compared with immune turbidimetry,the sensibitity of microalbumin test strips was 94.7% and the specificity was 86.4%.The total protein concentration of positive specimen detected by test strips were higher than negative specimen,the difference was significant(P<0.01).Conclusion The Conventional urine protein detection in the elderly physical examination was not meaningful.It was convenient and reliable to detect microalbuminuria using test strips and it was valuable in clinical application.

关 键 词：试带法 微量白蛋白 体检 

分 类 号：R446.1[医药卫生—诊断学] R446.6[医药卫生—临床医学]