糖芥总甙对豚鼠左心房生理特性的影响  

EFFECTS OF ERYSIUM CHEIRANTHOIDES L TOTAL CARDIAC GLYCOSIDES ON PHYSIOLOGICAL PROPERTIES OF GUINEA PIG LEFT ATRIA

作　　者：孙淑贤[1] 常福久[1] 王树林[1] 

机构地区：[1]黑龙江中医学院药理教研室,哈尔滨150040

出　　处：《中国药理学通报》1990年第5期314-316,共3页Chinese Pharmacological Bulletin

摘　　要：糖芥总甙(ETCG)对离体豚鼠左心房肌产生剂量依赖性的正性肌力作用,pD_2为7.94。ETCG(0.17mg/L)提高左心房肌兴奋性和肾上腺素诱发的自律性。ETCG(0.01～0.17mg/L)显著延长功能性不应期。Total cardiac glycosides isolated from dry fruit of Erysium chei- ranthoides L ( ETCG ) possesed positive inotropic effect. Its effects on the physiological properties of guinea pig left atria were studied. in this paper. The effects of ETCG on dose-response curve were investigated. The results showed that ETCG increased contractility of left atria significantly and dose-dependently .The pD2 value was 7.94. ETCG ( 0.17mg/L)increased significantly excitability and automaticity induced by epinephrine. ETCG(0....

关 键 词：糖芥总甙 左心房肌 收缩性 兴奋性 功能性不应期 自律性 

分 类 号：R96[医药卫生—药理学]