软珊瑚Sarcophyton sp.中一个新的西松烷二萜内酯的分离及结构测定  

Separation and Structural Determination of Structure of a New Cembranoid Lactone from the Soft Coral of Sarcophyton sp.

作　　者：马祥全[1] 闫素君[1] 苏镜娱[1] 曾陇梅[1] 

机构地区：[1]中山大学化学与化工学院,广州510275

出　　处：《高等学校化学学报》2004年第3期479-481,396,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 (批准号 :2 993 2 0 3 0 );高科技研究与发展计划海洋"八六三"计划 (批准号 :2 0 0 1AA62 0 40 3 )资助

摘　　要：Many cembranes, 14 membered ring diterpenoids, were reported to have antitumor and antimicrobial activities. Soft corals are rich sources of cembrenoid diterpenes. We reported cembrenoids lactones, such as sarcophinone, iso sarcophinone, sarcophine, sartrochine from the species of Sarcophyton in our earlier papers,. In continuation of our studies on the soft coral Sarcophyton , we obtained a new cembranoid lactone, named sarcophydiol(1) from a specimen of Sarcophyton sp . collected around the bay of Sanya, Hainan Island. On the basis of spectroscopic methods, its structure was determined as ( 10S *,11S *) 3,7,11α ,15 tetramethyl 10 β,11β dihydroxy cembr 2 E,6E,14(15)Z trien 16,1 olide(1). The bioactivities of compound 1 were under investigating.Many cembranes, 14 membered ring diterpenoids, were reported to have antitumor and antimicrobial activities. Soft corals are rich sources of cembrenoid diterpenes. We reported cembrenoids lactones, such as sarcophinone, iso sarcophinone, sarcophine, sartrochine from the species of Sarcophyton in our earlier papers,. In continuation of our studies on the soft coral Sarcophyton , we obtained a new cembranoid lactone, named sarcophydiol(1) from a specimen of Sarcophyton sp . collected around ...

关 键 词：软珊瑚 肉芝软珊瑚 二萜 西松烷内酯 

分 类 号：O629[理学—有机化学]