1-苯基-3-甲基-4-苯甲酰基-5-吡唑啉酮(HPMBP)缩甘氨酸甲酯的合成、表征和晶体结构  

Synthesis, Characterization and Crystal Structure of the Compound Derived from 1-Phenyl-3-methyl-4-benzoyl-5-pyrazolone (HPMBP) and Glycine Methyl Ester

作　　者：张欣[1] 朱华玲[1] 徐海珍[1] 王瑾玲[1] 

机构地区：[1]天津师范大学化学与生命科学学院,天津300074

出　　处：《有机化学》2004年第2期195-198,116,共5页Chinese Journal of Organic Chemistry

基　　金：天津市高等学校科技发展基金 (No.0 1 2 0 60 1 );天津市自然科学基金 (No.0 2 360 651 1 )资助项目

摘　　要：合成了化合物 1 苯基 3 甲基 4 苯甲酰基 5 吡唑啉酮 (HPMBP)缩甘氨酸甲酯 ,用红外光谱、核磁共振谱和元素分析等方法进行了表征 ,用X射线衍射方法测定了其晶体结构 .晶体学参数如下 :三斜晶系 ,空间群为P1,a =0 940 3 ( 3 )nm ,b =0 9884( 3 )nm ,c =1 0 12 7( 3 )nm ,α =86 666( 7)° ,β =89 82 7( 6)° ,γ =73 95 1( 6)° ,V =0 90 2 9( 5 )nm3 ,Z =2 ,Dc=1 2 85Mg·m-3 ,μ =0 0 88mm-1 ,F( 0 0 0 ) =3 68.最终偏离因子R1 =0 0 45 2 ,wR2 =0 0 889.A new compound derived from 1 phenyl 3 methyl 4 benzoyl 5 pyrazolone and glycine methyl ester has been synthesized and characterized by IR, 1H NMR spectra and elemental analysis. A full X ray crystal structure analysis of the compound has been performed. The crystal is Triclinic, space group is P 1, a =0 9403(3) nm, b =0 9884(3) nm, c =1 0127(3) nm, α =86 666(7)°, β =89 827(6)°, γ =73 951(6)°, V =0 9029(5) nm 3, Z = 2, D c=1 285 Mg·m -3 , μ =0...

关 键 词：1-苯基-3-甲基-4-苯甲酰基-5-吡唑啉酮 甘氨酸甲酯 合成 晶体结构 

分 类 号：O626[理学—有机化学]