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机构地区:[1]中国科学院南海海洋研究所广东省海洋药物重点实验室,广州510301
出 处:《天然产物研究与开发》2008年第1期1-4,共4页Natural Product Research and Development
基 金:This project was supported by the National Natural Science Foundation of China (grant:20502027);Hi-tech Research andDevelopment Program of China( grant:SQ2007AA09Z435255);Science and Technology Foundation of Guangdong Province
摘 要:从南海侧扁软柳珊瑚Subergorgia suberosa的二氯甲烷-甲醇提取物中首次分离鉴定了8个孕甾烷类化合物,经波谱鉴定为3β-O-palmitoyl-pregn-5-ene-20-one-3-ol(1),3β-O-palmitoyl-5α-pregn-20-one-3-ol(2),5α-pregn-1-ene-3,20-dione(3),3β,5α-pregn-20-one-3-ol(4),3β-pregn-5-ene-20-one-3-ol(5),3β,5β-pregn-20-one-3-ol(6),5β-pregn-3,20-dione(7),pregn-4-ene-3,20-dione(8)。其中化合物1,2为新化合物。Two new steroids,3β-O-palmitoyl-pregn-5-ene-20-one-3-ol (1),3β-O-palmitoyl-5α-pregn-20-one-3-ol (2),together with six known steroids,5α-pregn-1-ene-3,20-dione (3),3β,5α-pregn-20-one-3-ol (4),3β-pregn-5-ene-20-one-3-ol (5),3β,5β-pregn-20-one-3-ol (6),5β-pregn-3,20-dione (7),and pregn-4-ene-3,20-dione (8) were isolated from the CH2Cl2/MeOH extract of the South China Sea gorgonian coral Subergorgia suberosa,and identified on the basis of spectroscopic evidences and by comparison of the data reported.These comp...
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