加味苓桂术甘汤对腹泻型肠易激综合征肠道菌群的影响  

Effect of Linggui zhugan Decoction on Intestinal Flora of Diarrhea-predominate Irritable Bowel Syndrome

作　　者：江月斐[1] 劳绍贤[2] 邝枣园[2] 傅肖岩[3] 卞兆祥[4] 

机构地区：[1]福建中医学院中医系,福建福州350108 [2]广州中医药大学,广东广州510405 [3]福建中医学院附属第二人民医院,福建福州350003 [4]香港浸会大学

出　　处：《福建中医学院学报》2006年第6期7-9,共3页Journal of Fujian College of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(30271572)

摘　　要：观察加味苓桂术甘汤对腹泻型肠易激综合征脾虚证肠道菌群的影响。用加味苓桂术甘汤治疗腹泻型肠易激综合征脾虚证患者22例,并对治疗前后粪便中7种常见肠道细菌的变化进行研究。结果:①需氧菌与治疗前比较,脾虚证治疗后酵母菌明显下降(P<0.05),与正常组比较,无明显差异(P>0.05)。②厌氧菌与治疗前比较,脾虚证治疗后双歧杆菌、乳杆菌、拟杆菌、消化球菌明显上升(P<0.01);但与正常组比较,治疗后双歧杆菌、乳杆菌、消化球菌仍明显低于正常组(P<0.01),拟杆菌与正常组无明显差异(P>0.05)。结论:加味苓桂术甘汤对腹泻型肠易激综合征脾虚证患者肠道菌群失调可起一定的调整作用。To study the effect of linggui zhugan decoction on intestinal flora of diarrhea-predominate irritable bowel syndrome(IBS).22 cases of spleen deficiency syndrome of IBS were treated by the decoction and examined the intestinal flora of bacteria.The results showed that ①aerobe: yeast fungus was decreased obviously after treatment(P<0.05),and had no obvious difference compared with the normal group(P>0.05).②anaerobe: bifidobacteria,lactobacilli,bacteroid and peptococcus were increased obviously after tre...

关 键 词：苓桂术甘汤 腹泻型肠易激综合征 脾虚证 肠道菌群 

分 类 号：R259[医药卫生—中西医结合]