尖锐湿疣患者血清白介素10水平及其与白介素2关系的研究  

Study on the Serum Level of Interleukin10 and Its Relationship with Interleukin 2 in Patients with Condyloma Acuminatum

作　　者：廖镜云[1] 郭汉香[1] 

机构地区：[1]深圳市龙岗中心医院,广东深圳518116

出　　处：《实用医技杂志》2007年第7期827-828,共2页Journal of Practical Medical Techniques

摘　　要：目的为了研究白介素(IL)10在尖锐湿疣(CA)发病机制中的作用及其与IL-2的关系。方法我们采用双抗体夹心ELISA技术检测24例CA患者血清IL-10水平,其中19例同时作IL-2水平测定。结果发现CA患者血清IL-10水平比正常人显著增高(P<0.05),IL-2水平降低(P<0.05);IL-10与IL-2间呈负相关性(r=-0.894,P<0.001),说明IL-10对IL-2产生有明显的抑制作用。结论本实验证明,CA患者存在着细胞因子产生失衡所引起的一系列细胞免疫反应抑制效应,在CA发病机制中起着重要作用。Objetive In order to study the role of interleukin(IL)10 in pathogenesis of condylona acumina-tum(CA) and relationship between IL 10 and IL 2. MethodsWe used double antibody sandwich ELISA for the quantitative determination of serum IL 10 level in 24 patients with CA.Among them,serum IL 2 level in 19 patients was also measured simultaneously.Results The results showed the serum IL 10 level was signify-cantly(P<0.05) higher in CA patients than that of controls,and the serum IL 2 level was strikingly (P<...

关 键 词：尖锐湿疣 白介素10 白介素2 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]