Oddi括约肌功能失调的药物与内镜治疗的作用  

Efficiency of drug and endosepic sphincterotomy for sphincter of Oddi dysfunction

作　　者：徐章[1] 胡阳黔[1] 丁百静[1] 刘祖明[1] 南丽艳[1] 

机构地区：[1]郧阳医学院附属东风总医院消化科,湖北十堰442008

出　　处：《临床肝胆病杂志》2007年第3期203-204,共2页Journal of Clinical Hepatology

摘　　要：了解药物与内镜下十二指肠乳头括约肌切开术(EST)对胆囊切除术后Odd i括约肌功能失调(SOD)的疗效。以临床诊断的SOD患者先行药物治疗一周,无效者再行EST治疗,观察其疗效。在45例药物治疗的患者中,有效者仅11例,其有效率为24.4%;而在34例药物治疗无效后经EST治疗的患者中,有效者为31例,其有效率为91.2%,明显优于药物治疗(P<0.005)。EST术中和术后出现并发症4例,其发生率为11.8%。EST是药物治疗SOD无效时的最佳手段。To investigate the effects of drug and endoscopic sphincterotomy(EST) in post-cholecystectomy patients with sphincter of Oddi dysfunction(SOD) 45 cases with SOD,which had been diagnosed clinically,were divided into two groups.All the 45 patients were treated with drug initially.Then 34 patients who had no response to drug treatment were treated with EST one week later.The utility rate of drug group and EST group is 24.4%(11/45) and 91.2%(31/34) respectively.The therapeutic effect of EST group was significantly higher than that of drug group(P<0.005).In EST group,4 patients(11.8%;4/34) had complications during or after EST operation.EST is the best therapeutic method for SOD,especially when drug has no efficiency.

关 键 词：ODDI括约肌功能失调 药物治疗 内镜下乳头括约肌切开术 

分 类 号：R657.4[医药卫生—外科学]