心肌肌钙蛋白在川崎病冠状动脉病变诊断中的价值  

Values of cardiac troponin Ⅰ in the assessment of coronary artery lesions in Kawsaki disease

作　　者：朱章华[1] 吕进泉[1] 王锁英[1] 韩晓玲[1] 

机构地区：[1]江苏大学附属医院儿科,江苏镇江212001

出　　处：《现代医学》2007年第6期442-443,共2页Modern Medical Journal

摘　　要：目的探讨血清心肌肌钙蛋白(cTnⅠ)在川崎病冠状动脉病变中的变化及其临床意义。方法检测川崎病患儿血清cTnⅠ水平,对川崎病并发冠状动脉病变(CAL)组和无冠状动脉病变(NCAL)组患儿治疗前后的血清cTnⅠ水平进行对比分析。结果川崎病患儿治疗前血清cTnⅠ水平明显高于治疗后,CAL组明显高于NCAL组。结论血清cTnⅠ既可作为一种早期诊断川崎病患儿心肌损害的特异性指标,也可作为观察川崎病患儿大剂量丙种球蛋白治疗后判定疗效的指标。Objective To explore the changes of cardiac troponin I(cTnⅠ) in Kawsaki disease(KD) with coronary artery lesions(CAL) and its clinical values.Methods The levels of cTnⅠ of children with KD supervening CAL and non-supervening CAL were determined before and after treatment.Results The levels of cTnⅠ in KD children before treatment were significantly higher than those after treatment,and in CAL group the levels of cTnⅠ were significantly higher than those in non-coronary artery lesions(NCAL) group.Conclusions cTnⅠnot only is a special testing item of myocardial lesions in KD in early stage but also is an index of curative effect after using large dose of intravenous gamona-globulin.

关 键 词：肌钙蛋白 川崎病 冠状动脉病变 

分 类 号：R725[医药卫生—儿科]