无水酒精联合利多卡因治疗小儿淋巴管瘤  

absolute alcohol and lidocaine on lymphangioma in children

作　　者：胡元军[1] 孙大庆[2] 于旸[1] 张宗瑞[1] 冯立林[1] 

机构地区：[1]山东大学齐鲁儿童医院,山东济南250022 [2]山东大学第二医院

出　　处：《山东医药》2007年第18期5-6,共2页Shandong Medical Journal

摘　　要：目的探讨无水酒精联合利多卡因治疗淋巴管瘤的临床效果。方法将238例淋巴管瘤患儿随机分为两组,一组用无水酒精联合利多卡因治疗(无水酒精组),一组用糖皮质激素治疗(激素组)．观察其疗效。结果无水酒精组治愈率为92．8%．有效率为100%;激素组治愈率为65．7%,有效率为93．9%。两组比较．P均＜0．01。无水酒精组治疗后病理检查为淋巴管腔消失或大致恢复正常;两组治疗后B超均显示未探及液性暗区．有不均质的片状及斑片状回声。结论无水酒精联合利多卡因治疗淋巴管瘤治愈率高,无明显不良反应。[Objective]To discuss the clinical outcome of treatment of lymphangioma in children with absolute alcohol and lidocaine directly administered into the tumor.[Methods]238 outpatients were randomly assigned to 2 groups:the treatment group(absolute alcohol and lidocaine)and the control group(glucocorticoid).Both groups underwent direct injection on the site of lymphangioma with different dosages and medications according to the different subtypes.The efficiency ratio and curability ratio were measured by comparision between the 2 groups by statistic analysis.[Results]In the treatment group of 139 patients,the total effective ratio was 100% with the total curability ratio of 92.8%.Among the control group of 99 patients,the curability ratio was 65.7% with the effective ratio of 93.9%.The data from 2 groups were analysed byχ~2 test.The result showed an obvious difference(P＜0.01).Lymphatic cavity disappeared or resumed after treated with absolute alcohol,B-ultrasound found no liquid dark area in both groups,and there were non-homogenized echoes.[Conclusions]Treatment of lymphangioma with absolute alcohol and lidocaine in children has a marked effectiveness within the safe dosage range and it has high curability rate with no obvious adverse effect.

关 键 词：淋巴管瘤 无水酒精 利多卡因 注射疗法 

分 类 号：R452[医药卫生—治疗学] R733[医药卫生—临床医学]