中医辨证联合HAART疗法治疗HIV/AIDS临床观察  

Clinical observation on integrated treatment of traditional Chinese Medicine and HAART therapy on HIV/AIDS

作　　者：张爱民[1] 谭行华[1] 岑玉文[1] 倪仁芳[1] 陈铿[1] 陈明[1] 王淑梅[1] 谢敏[1] 贾卫东[1] 

机构地区：[1]广东省广州市第八人民医院中西医结合科,广东广州510060

出　　处：《河北中医》2007年第10期874-877,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：广东省中医药局科研立项课题(编号:1050060)

摘　　要：目的观察中医辨证联合HAART疗法治疗艾滋病感染者和患者(HIV/AIDS)的临床疗效。方法选择符合入选标准的HIV/AIDS患者63例,随机分成3组。中药组20例,采用中医辨证治疗;中西医结合组22例,采用中医辨证联合HAART疗法治疗;西药组21例,单用HAART疗法治疗。记录治疗前后各组患者症状体征积分、卡洛夫斯基积分及CD4细胞计数、HIV-RNA载量,并进行比较。结果治疗后,中西医结合组、西药组CD4细胞计数、HIV-RNA载量及卡洛夫斯基积分明显好转,与治疗前及中药组治疗后比较差异均有统计学意义(P<0.05);中药组CD4细胞计数、卡洛夫斯基积分治疗后好转,但与治疗前比较差异无统计学意义(P>0.05),HIV-RNA载量较前上升。治疗后3组症状、体征较治疗前均有好转,但3组有效率差异无统计学意义(P>0.05)。结论中医辨证联合HAART疗法较单纯中药或单纯HAART疗法能更有效地提高HIV/AIDS患者细胞免疫功能,降低HIV-RNA载量,改善患者症状体征,提高生活质量。Objective To explore the clinical effect of integrated treatment of traditional Chinese medicine and HAART therapy on HIV/AIDS.Methods The 63 cases of HIV/AIDS were divided into 3 groups randomly.20 cases in group A were treated with traditional Chinese medicine, 22 cases in group B were treated with traditional Chinese medicine and HAART therapy, 21 cases in group C were treated only with HAART treatment. Clinical scores, CD4 cell count, HIV-RNA count in the sputum before and after treatment were investigated.Results The CD4, Karnovsky Score level of group B, C were improved significantly (P<0.01) compared with those in group A. HIV-RNA count has descend quickly compared with that of the group A. Clinical scores were improved 73.7% in group A, 80% in group B, 65% in group C. And there was no significantly difference among 3 groups.Conclusion Integrated treatment of Traditional Chinese Medicine and HAART therapy has obvious effect on HIV/AIDS.

关 键 词：HIV感染 获得性免疫缺陷综合征 抗病毒药 抗逆转录病毒治疗 高效 辨证施治 

分 类 号：R289.6[医药卫生—方剂学] R45[医药卫生—中药学] R453[医药卫生—中医学] R512.910.58