Study on the Interaction between Distamycin Analogs and DNA from Herring Sperm by Fluorimetry  

作　　者：Han LIANG Jing Jian LI Xiao Dong LI Fei Li TANG Gu YUAN 

机构地区：[1]Department of Chemistry,Peking University,Beijing 100871 [2]The Key Laboratory of Bioorganic Chemistry and Molecular Engineering,Department of Chemical Biology,Peking University,Beijing 100871

出　　处：《Chinese Chemical Letters》2002年第10期1001-1002,共2页中国化学快报(英文版)

基　　金：The project was supported by the National Natural Science Foundation of China (No.39970169,29872001).

摘　　要：The fluorescence spectra of the interaction between four new distamycin analogs and DNA from herring sperm have been studied in detail. The fluorescence quenching of the DNA by the analogs was observed, and the fluorescence intensity of the DNA was attenuated exponentially with the increasing of the analogs concentration.The fluorescence spectra of the interaction between four new distamycin analogs and DNA from herring sperm have been studied in detail. The fluorescence quenching of the DNA by the analogs was observed, and the fluorescence intensity of the DNA was attenuated exponentially with the increasing of the analogs concentration.

关 键 词：Distamycin analogs fluorescence quenching DNA from herring sperm. 

分 类 号：Q523[生物学—生物化学]