氯诺昔康和曲马多在颅脑手术后镇痛的对比研究  

Contrast Research on Tramadol and Lornoxicam used for Patient Controlled Intravenous Analgesia after Craniotomy

作　　者：王卓丹[1] 高崇荣[1] 黄焕森[1] 

机构地区：[1]广州医学院第二附属医院,广东广州510260

出　　处：《实用医技杂志》2008年第11期1361-1363,共3页Journal of Practical Medical Techniques

摘　　要：目的:观察氯诺昔康和曲马多用于颅脑手术后患者自控镇痛(PCIA)的效果和不良反应。方法:60例ASAⅠ级~Ⅱ级择期颅脑手术患者,采用随机、对照的方法将患者分为两组,每组30例。L组用氯诺昔康PCIA;Q组用曲马多PCIA。术后患者完全清醒后静脉连接PCA泵。术后接泵即刻、术后4h、12h、24h、48h分别观察VAS评分;Ramesay镇静评分、Glasgow昏迷评分;恶心、呕吐、眩晕、异常出血等不良反应。结果:氯诺昔康组和曲马多组镇痛效果相近;氯诺昔康组患者不良反应较少。结论:氯诺昔康用于颅脑术后患者PCIA是安全、有效的,不良反应发生率低于曲马多。Objective To compare the effect and side effect with tramadol and lornoxicam used for patient controlled intravenous analgesia .Methods 60 adult patients which scheduled for elective craniotomy with general anesthesia were randomly divided into two groups with 30 patients in each group.When they awaked in the recovery room ,they received drugs by titration to achieve analgesia。Group lornoxicam (group L),continuous infusion 0.4 mg/h,PCA bolus 2 mg,lockout time 30 min; group tramadol (group Q),continuous infu...

关 键 词：氯诺昔康 曲马多 颅脑手术 患者静脉自控镇痛 

分 类 号：R614[医药卫生—麻醉学]